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浏览/检索结果: 共24条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Wu, Bing;  Xu, Meng-meng;  Fan, Chen;  Feng, Chun-lan;  Lu, Qiu-kai 收藏  |  浏览/下载：62/0  |  提交时间：2022/01/18 acute lung injury  STING  vascular endothelial cells  inflammatory cytokines  chemokines  chemotaxis   Impurity Identification and Scale-Up of a Novel Glycopeptide Antibiotic 期刊论文 ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2390-2402 作者:  Jiao, Shang;  Guan, Dongliang;  Xu, Lili;  Liu, Bo;  Shi, Weiwei 收藏  |  浏览/下载：19/0  |  提交时间：2022/01/18 glycopeptide antibiotics  impurity  analytical method  process optimization and development   SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade 期刊论文 EMBO JOURNAL, 2021, 页码: 16 作者:  Wang, Xu;  Ni, Jiahui;  You, Yan;  Feng, Guize;  Zhang, Sulin 收藏  |  浏览/下载：40/0  |  提交时间：2021/12/16 E-cadherin  IBD  intestinal barrier function  LPS release  SNX10   Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文 JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251 作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen 收藏  |  浏览/下载：92/0  |  提交时间：2021/11/04 PDE4  Arctigenin  Psoriasis  Inflammation   Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11 作者:  Li, Bo;  Li, Heng;  Zhu, Zhengdan;  Xiang, Caigui;  Xu, Zhijian 收藏  |  浏览/下载：106/0  |  提交时间：2021/11/04 Anti-inflammatory activity  TNF alpha  ER beta  IBD Arylisoquinolones   Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells 期刊论文 ADVANCED FUNCTIONAL MATERIALS, 2021, 页码: 14 作者:  Duan, Nianxiu;  Li, Junjun;  Song, Sha;  Wang, Feng 收藏  |  浏览/下载：29/0  |  提交时间：2021/11/04 drug delivery  pancreatic cancer  prodrugs  smart liposomes  tumor-specific vascular promotion   Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation 期刊论文 PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11 作者:  Bao, Weilian;  Liu, Xiaohong;  You, Yan;  Hou, Hui;  Wang, Xu 收藏  |  浏览/下载：58/0  |  提交时间：2021/11/16 SNX10  IBD  Macrophage  PIKfyve  TBK1  PPI inhibitor   Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12 作者:  Su, Haixia;  Yao, Sheng;  Zhao, Wenfeng;  Zhang, Yumin;  Liu, Jia 收藏  |  浏览/下载：33/0  |  提交时间：2021/08/17 SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文 CELL RESEARCH, 2021, 页码: 14 作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang 收藏  |  浏览/下载：85/0  |  提交时间：2021/08/17 Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14 作者:  Yang, Xiangbo;  Wang, Zhijia;  Pei, Yuan;  Song, Ning;  Xu, Lei 收藏  |  浏览/下载：42/0  |  提交时间：2021/08/17 SHP2 degradation  Proteolysis targeting chimera (PROTAC)  Thalidomide-based heterobifunctional molecules  E3 ubiquitin ligase  CRBN