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浏览/检索结果: 共8条，第1-8条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090 作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan 收藏  |  浏览/下载：24/0  |  提交时间：2022/01/04 Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Wang, Lin;  Wu, Yan;  Yao, Sheng;  Ge, Huan;  Zhu, Ya 收藏  |  浏览/下载：88/0  |  提交时间：2021/11/04 SARS-CoV-2  natural products  virtual screening  spike protein  protein-protein interaction modulators   Detachable Liposomes Combined Immunochemotherapy for Enhanced Triple-Negative Breast Cancer Treatment through Reprogramming of Tumor-Associated Macrophages 期刊论文 NANO LETTERS, 2021, 卷号: 21, 期号: 14, 页码: 6031-6041 作者:  Chen, Mingshu;  Miao, Yunqiu;  Qian, Kun;  Zhou, Xin;  Guo, Linmiao 收藏  |  浏览/下载：28/0  |  提交时间：2021/11/04 Immunochemotherapy  triple-negative breast cancer  liposomes  tumor-associated macrophages  MMP2 response   Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 12 作者:  Zhang, Hui;  Chen, Kun;  Tan, Qiuxiang;  Shao, Qiang;  Han, Shuo 收藏  |  浏览/下载：50/0  |  提交时间：2021/08/17 Cinnacetals A and B: Two highly oxidated and modified isoryanodane diterpenoids from Cinnamomum cassia 期刊论文 TETRAHEDRON LETTERS, 2021, 卷号: 73, 页码: 5 作者:  Huang, Yi-Qi;  Zhou, Bin;  Yuan, Yu-Rong;  Ren, Yu-Hao;  Li, Dong-Li 收藏  |  浏览/下载：13/0  |  提交时间：2021/08/17 Cinnamomum cassia  Isoryanodane diterpenoid  X-ray crystallography  ECD calculation  Biosynthetic pathway   Aristolochic acid I promoted clonal expansion but did not induce hepatocellular carcinoma in adult rats 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Liu, Yong-zhen;  Lu, Heng-lei;  Qi, Xin-ming;  Xing, Guo-zhen;  Wang, Xin 收藏  |  浏览/下载：72/0  |  提交时间：2021/05/24 aristolochic acid I  glutathione S-transferase placental form-positive foci  clonal expansion  hepatocellular carcinoma  medium-term rat liver bioassay  DNA adducts   Reply to: Binding site for MDL-801 on SIRT6 期刊论文 NATURE CHEMICAL BIOLOGY, 2021, 页码: 5 作者:  Huang, Zhimin;  Zhao, Junxing;  Deng, Wei;  Chen, Yingyi;  Shang, Jialin 收藏  |  浏览/下载：64/0  |  提交时间：2021/05/24 Development of a nanobody-based immunoassay for the sensitive detection of fibrinogen-like protein 1 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Zhang, Wan-ting;  Liu, Ting-ting;  Wu, Man;  Chen, Xiao-chen;  Han, Li 收藏  |  浏览/下载：53/0  |  提交时间：2021/05/24 nanobody  FGL1  cancer immunology  diagnosis  immune checkpoint