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浏览/检索结果: 共31条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Remodeling immune microenvironment in periodontitis using resveratrol liposomes as an antibiotic-free therapeutic strategy 期刊论文 Journal of Nanobiotechnology, 2021, 卷号: 19, 期号: 1 作者:  Shi,Junyu;  Zhang,Yi;  Zhang,Xiaomeng;  Chen,Ruiying;  Wei,Jianxu 收藏  |  浏览/下载：46/0  |  提交时间：2022/01/04 Resveratrol  Macrophage  Periodontitis  Liposome  Immune microenvironment  Local delivery   LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang 收藏  |  浏览/下载：62/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11 作者:  Cheng, Zhiyang;  Huang, Ying;  Shen, Qianqian;  Zhao, Yangrong;  Wang, Lei 收藏  |  浏览/下载：87/0  |  提交时间：2021/11/04 Cancer  beta-glucuronidase  Bioconjugation  Albumin  Camptothecin   Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1 期刊论文 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14 作者:  Zhang, Chun;  Sun, Yi-Tao;  Gao, Li-Xin;  Feng, Bo;  Yan, Xue 收藏  |  浏览/下载：21/0  |  提交时间：2022/01/18 Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy 期刊论文 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635 作者:  Wu, Aihua;  Chen, Yingzhi;  Wang, Hairui;  Chang, Ya;  Zhang, Meng 收藏  |  浏览/下载：27/0  |  提交时间：2022/01/18 Trichosanthin  Legumain  TRP2  Transcutaneous immunization  Adjuvant  Cancer vaccine  Protein engineering   Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13 作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun 收藏  |  浏览/下载：31/0  |  提交时间：2021/12/01 2,5-diphenyl-1,3,4-oxadiazole derivatives  SHP2  Inhibitors  Structure-activity relationships (SAR)   Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090 作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan 收藏  |  浏览/下载：24/0  |  提交时间：2022/01/04 5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19 作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing 收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04 NSD2  Methyltransferase  HTS  Multiple myeloma  5-Aminonaphthalene derivatives  Inhibitor   Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847 作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing 收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16 Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663 作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong 收藏  |  浏览/下载：17/0  |  提交时间：2021/12/16