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浏览/检索结果: 共94条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Remodeling immune microenvironment in periodontitis using resveratrol liposomes as an antibiotic-free therapeutic strategy 期刊论文 Journal of Nanobiotechnology, 2021, 卷号: 19, 期号: 1 作者:  Shi,Junyu;  Zhang,Yi;  Zhang,Xiaomeng;  Chen,Ruiying;  Wei,Jianxu 收藏  |  浏览/下载：48/0  |  提交时间：2022/01/04 Resveratrol  Macrophage  Periodontitis  Liposome  Immune microenvironment  Local delivery   A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11 作者:  Cheng, Zhiyang;  Huang, Ying;  Shen, Qianqian;  Zhao, Yangrong;  Wang, Lei 收藏  |  浏览/下载：87/0  |  提交时间：2021/11/04 Cancer  beta-glucuronidase  Bioconjugation  Albumin  Camptothecin   GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui 收藏  |  浏览/下载：47/0  |  提交时间：2022/01/18 GPR84  medium chain fatty acid receptor  GPCR  inflammatory bowel diseases  ulcerative colitis  NLRP3 inflammasome  macrophages   STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Wu, Bing;  Xu, Meng-meng;  Fan, Chen;  Feng, Chun-lan;  Lu, Qiu-kai 收藏  |  浏览/下载：61/0  |  提交时间：2022/01/18 acute lung injury  STING  vascular endothelial cells  inflammatory cytokines  chemokines  chemotaxis   Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo 收藏  |  浏览/下载：43/0  |  提交时间：2022/01/18 DPP4  distal mutation  enzymatic activity  molecular dynamics simulation  structure-function mechanism   Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence 期刊论文 NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089 作者:  Bai, Xiangd;  Wang, Hanchen;  Ma, Liya;  Xu, Yongchao;  Gan, Jiefeng 收藏  |  浏览/下载：52/0  |  提交时间：2022/01/18 Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Dong, Ying;  Tang, Bi-xi;  Wang, Qi;  Zhou, Li-wei;  Li, Cong 收藏  |  浏览/下载：81/0  |  提交时间：2022/01/04 idiopathic pulmonary fibrosis  DDRs  kinase inhibitor  indazole derivatives  XBLJ-13  nintedanib  bleomycin-induced pulmonary fibrosismouse model   Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文 ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452 作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui 收藏  |  浏览/下载：30/0  |  提交时间：2022/01/04 Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity 期刊论文 ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22 作者:  Hu, Lin;  Chen, Fuxian;  Wu, Chao;  Wang, Jun;  Chen, Si-si 收藏  |  浏览/下载：39/0  |  提交时间：2022/01/18 SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy 期刊论文 JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306 作者:  Huang, Ying;  Wang, Lei;  Cheng, Zhiyang;  Yang, Biyu;  Yu, Jiahui 收藏  |  浏览/下载：24/0  |  提交时间：2021/12/01 Antitumour  Chemotherapy  SN38  Drug delivery systems  Albumin