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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文 MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206 作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen 收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16 Progression and Regression of Abdominal Aortic Aneurysms in Mice 期刊论文 CURRENT MEDICAL SCIENCE, 2021, 页码: 8 作者:  Ding, Yu-chao;  Zhang, Xian-jing 收藏  |  浏览/下载：28/0  |  提交时间：2021/12/01 abdominal aortic aneurysm  disease progression  disease regression  elastogenesis  lysyl oxidase   Constitutive signal bias mediated by the human GHRHR splice variant 1 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10 作者:  Cong, Zhaotong;  Zhou, Fulai;  Zhang, Chao;  Zou, Xinyu;  Zhang, Huibing 收藏  |  浏览/下载：27/0  |  提交时间：2021/12/01 class B1 GPCR  receptor bias  cancer  cell proliferation   Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 32, 页码: 8 作者:  Wang, Xi;  Cheng, Xi;  Zhao, Lihua;  Wang, Yuzhe;  Ye, Chenyu 收藏  |  浏览/下载：27/0  |  提交时间：2021/11/04 parathyroid hormone receptor 2  cryo-electron microscopy  G protein-coupled receptor  ligand recognition  syndromic short stature   Blood Pyrrole-DNA Adducts Define the Early Tumorigenic Risk in Patients with Pyrrolizidine Alkaloid-Induced Liver Injury 期刊论文 ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2021, 卷号: 8, 期号: 7, 页码: 551-557 作者:  He, Yisheng;  Zhang, Wei;  Ma, Jiang;  Xia, Qingsu;  Song, Zijing 收藏  |  浏览/下载：27/0  |  提交时间：2021/08/17 SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文 CELL RESEARCH, 2021, 页码: 14 作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang 收藏  |  浏览/下载：82/0  |  提交时间：2021/08/17 Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan 收藏  |  浏览/下载：83/0  |  提交时间：2021/06/11 glyceraldehyde 3-phosphate dehydrogenase  1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Li, Wen;  Liao, Li-ping;  Song, Ning;  Liu, Yan-jun;  Ding, Yi-luan 收藏  |  浏览/下载：82/0  |  提交时间：2021/06/11 glyceraldehyde 3-phosphate dehydrogenase  1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose  hydrogen deuterium exchange mass spectrometry  reversible inhibitor  glycolysis   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen 收藏  |  浏览/下载：154/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794 作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu 收藏  |  浏览/下载：48/0  |  提交时间：2021/05/24 Tyrosine kinase  Covalent FGFR inhibitors  Virtual screening  Pyrazolo[3,4-d] pyridazinone  Structure-activity relationships  Antitumor efficacy