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科研机构
上海药物研究所 [14]
内容类型
期刊论文 [14]
发表日期
2021 [14]
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浏览/检索结果:
共14条,第1-10条
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发表日期:2021
专题:上海药物研究所
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Enones as Alkenyl Reagents via Ligand-Promoted C-C Bond Activation
期刊论文
ACS CATALYSIS, 2021, 页码: 82-88
作者:
Li, Hanyuan
;
Wang, Mei-Ling
;
Liu, Yu-Wen
;
Li, Ling-Jun
;
Xu, Hui
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/01/18
C-C bond activation
enone
olefination
Pd-catalyzed
late-stage diversification
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Chen, Cheng
;
Ren, Yong-mei
;
Zhu, Jian-zhong
;
Chen, Jia-li
;
Feng, Zhe-ling
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/01/04
Ainsliadimer C
interleukin-1 beta
macrophages
NLRP3 inflammasome
Sirtuin 1
adipose tissue inflammation
obesity
metabolic disorders
EX-527
dexamethasone
Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence
期刊论文
CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21
作者:
Zan, Gui-Ying
;
Wang, Yu-Jun
;
Li, Xue-Ping
;
Fang, Jun-Fan
;
Yao, Song-Yu
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/12/16
Rhodomeroterpene alleviates macrophage infiltration and the inflammatory response in renal tissue to improve acute kidney injury
期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 11, 页码: 17
作者:
Wu, Yong-Mei
;
Shi, Qing
;
Zhu, Peng-Fei
;
Ma, Hai-Jian
;
Cui, Shi-Chao
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/12/16
acute kidney injury
IKK/NF-kappa B
inflammation
macrophage
PI3K/PDK1/Akt
rhodomeroterpene
Structural insights into the activation of human calcium-sensing receptor
期刊论文
ELIFE, 2021, 卷号: 10, 页码: 24
作者:
Chen, Xiaochen
;
Wang, Lu
;
Cui, Qianqian
;
Ding, Zhanyu
;
Han, Li
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/11/04
G-protein-coupled receptor
calcium-sensing receptor
cryo-electron microscopy
calcium ions
nanobody
CaSR
GPCR
cryo-EM
None
BCL9 regulates CD226 and CD96 checkpoints in CD8(+) T cells to improve PD-1 response in cancer
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 14
作者:
Feng, Mei
;
Wu, Zhongen
;
Zhou, Yan
;
Wei, Zhuang
;
Tian, Enming
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/11/04
Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-)Rag2(-/-)IL2rg(-/-) Rats
期刊论文
ADVANCED SCIENCE, 2021, 页码: 14
作者:
Zhang, Ludi
;
Ge, Jian-Yun
;
Zheng, Yun-Wen
;
Sun, Zhen
;
Wang, Chenhua
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
bioreactor
humanized liver
liver xeno-repopulation
pharmacological study
Preferential Targeting Cerebral Ischemic Lesions with Cancer Cell-Inspired Nanovehicle for Ischemic Stroke Treatment
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 7, 页码: 3033-3043
作者:
He, Wenxiu
;
Mei, Qiyong
;
Li, Jie
;
Zhai, Yuting
;
Chen, Yiting
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/06/11
ischemic stroke
blood-brain barrier
bioinspired nanovehicle
cell membrane
drug delivery
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