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浏览/检索结果: 共14条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui;  Fang, You-chen;  Wang, Si-wei 收藏  |  浏览/下载：47/0  |  提交时间：2022/01/18 GPR84  medium chain fatty acid receptor  GPCR  inflammatory bowel diseases  ulcerative colitis  NLRP3 inflammasome  macrophages   Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity 期刊论文 ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22 作者:  Hu, Lin;  Chen, Fuxian;  Wu, Chao;  Wang, Jun;  Chen, Si-si 收藏  |  浏览/下载：40/0  |  提交时间：2022/01/18 Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence 期刊论文 CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21 作者:  Zan, Gui-Ying;  Wang, Yu-Jun;  Li, Xue-Ping;  Fang, Jun-Fan;  Yao, Song-Yu 收藏  |  浏览/下载：46/0  |  提交时间：2021/12/16 Oxidized Low-Density Lipoprotein Links Hypercholesterolemia and Bladder Cancer Aggressiveness by Promoting Cancer Stemness 期刊论文 CANCER RESEARCH, 2021, 卷号: 81, 期号: 22, 页码: 5720-5732 作者:  Yang, Lin;  Sun, Jingya;  Li, Meiqian;  Long, Yiming;  Zhang, Dianzheng 收藏  |  浏览/下载：24/0  |  提交时间：2022/01/04 Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219 作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu 收藏  |  浏览/下载：42/0  |  提交时间：2021/12/01 Hippo pathway  TEAD3  Covalent inhibitor  Palmitoylation inhibitor   Kynurenine derivative 3-HAA is an agonist ligand for transcription factor YY1 期刊论文 Journal of Hematology & Oncology, 2021, 卷号: 14, 期号: 1 作者:  Shi,Zhaopeng;  Gan,Guifang;  Xu,Xiang;  Zhang,Jieying;  Yuan,Yuan 收藏  |  浏览/下载：47/0  |  提交时间：2021/11/04 3-Hydroxyanthronic acid (3-HAA)  Kynurenine  YY1  DUSP6  Hepatocellular carcinoma (HCC)  Tryptophan metabolism   A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor 期刊论文 JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8 作者:  Zhou, Jun;  Zhan, Yan;  Zhong, Dafang;  Chen, Xiaoyan;  Zhang, Yifan 收藏  |  浏览/下载：74/0  |  提交时间：2021/11/04 chimmitecan  mass spectrometry  pharmacokinetics  simmitecan  solid tumors   Discovery of High-Affinity Inhibitors of the BPTF Bromodomain 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12075-12088 作者:  Lu, Tian;  Lu, Haibo;  Duan, Zhe;  Wang, Jun;  Han, Jie 收藏  |  浏览/下载：38/0  |  提交时间：2021/11/04 Amygdala dynorphin/kappa opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Zan, Gui-ying;  Sun, Xiang;  Wang, Yu-jun;  Liu, Rui;  Wang, Chen-yao 收藏  |  浏览/下载：29/0  |  提交时间：2021/08/17 depression  social defeat stress  amygdala  κ  opioid receptor  dynorphin  c-fos  ERK  norBNI   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen 收藏  |  浏览/下载：155/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial