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科研机构
上海药物研究所 [16]
内容类型
期刊论文 [16]
发表日期
2021 [16]
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浏览/检索结果:
共16条,第1-10条
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发表日期:2021
专题:上海药物研究所
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Conformational polymorphs of isotretinoin and their impact on physicochemical and biological properties
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 610, 页码: 10
作者:
Cheng, Yinxiang
;
Rong, Xiaoyi
;
Xia, Mengyuan
;
Zhang, Zaiyong
;
Wang, Jian-Rong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/01/04
Polymorph
Isotretinoin
Stability
Solubility
Bioavailability
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Chen, Cheng
;
Ren, Yong-mei
;
Zhu, Jian-zhong
;
Chen, Jia-li
;
Feng, Zhe-ling
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2022/01/04
Ainsliadimer C
interleukin-1 beta
macrophages
NLRP3 inflammasome
Sirtuin 1
adipose tissue inflammation
obesity
metabolic disorders
EX-527
dexamethasone
Progression and Regression of Abdominal Aortic Aneurysms in Mice
期刊论文
CURRENT MEDICAL SCIENCE, 2021, 页码: 8
作者:
Ding, Yu-chao
;
Zhang, Xian-jing
;
Zhang, Ji-xiu
;
Zhai, Zi-yi
;
Zhang, Mei-xia
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/01
abdominal aortic aneurysm
disease progression
disease regression
elastogenesis
lysyl oxidase
Improving Stability of Vitamin B5 Through Double Salt Formation
期刊论文
CRYSTAL GROWTH & DESIGN, 2021, 卷号: 21, 期号: 9, 页码: 4997-5005
作者:
Liang, Xuan
;
Zhang, Qi
;
Zhang, Zaiyong
;
Ding, Qiaoce
;
Mei, Xuefeng
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/11/04
Structural insights into the activation of human calcium-sensing receptor
期刊论文
ELIFE, 2021, 卷号: 10, 页码: 24
作者:
Chen, Xiaochen
;
Wang, Lu
;
Cui, Qianqian
;
Ding, Zhanyu
;
Han, Li
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/11/04
G-protein-coupled receptor
calcium-sensing receptor
cryo-electron microscopy
calcium ions
nanobody
CaSR
GPCR
cryo-EM
None
Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:
Chen, Zhen-dong
;
Chen, Qian
;
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Zhan, Yan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/04
henagliflozin
food effects
mass balance
pharmacokinetics
SGLT-2 inhibitor
Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-)Rag2(-/-)IL2rg(-/-) Rats
期刊论文
ADVANCED SCIENCE, 2021, 页码: 14
作者:
Zhang, Ludi
;
Ge, Jian-Yun
;
Zheng, Yun-Wen
;
Sun, Zhen
;
Wang, Chenhua
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
bioreactor
humanized liver
liver xeno-repopulation
pharmacological study
Preferential Targeting Cerebral Ischemic Lesions with Cancer Cell-Inspired Nanovehicle for Ischemic Stroke Treatment
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 7, 页码: 3033-3043
作者:
He, Wenxiu
;
Mei, Qiyong
;
Li, Jie
;
Zhai, Yuting
;
Chen, Yiting
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/06/11
ischemic stroke
blood-brain barrier
bioinspired nanovehicle
cell membrane
drug delivery
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