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科研机构
上海药物研究所 [19]
内容类型
期刊论文 [19]
发表日期
2021 [19]
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发表日期:2021
专题:上海药物研究所
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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:
Fan, Shijie
;
Yue, Liyan
;
Wan, Wei
;
Zhang, Yuanyuan
;
Zhang, Bidong
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/12/16
covalent modification
probes
proteome
LC3
post-translational modification
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:
Chen, Yun
;
Bai, Gang
;
Li, Yan
;
Ning, Yi
;
Cao, Sufen
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/12/01
FLT3
FLT3-ITD
Acute myeloid leukemia
Structure-activity relationships
Pyrazolo[1, 5-a]pyrimidine
Progression and Regression of Abdominal Aortic Aneurysms in Mice
期刊论文
CURRENT MEDICAL SCIENCE, 2021, 页码: 8
作者:
Ding, Yu-chao
;
Zhang, Xian-jing
;
Zhang, Ji-xiu
;
Zhai, Zi-yi
;
Zhang, Mei-xia
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/01
abdominal aortic aneurysm
disease progression
disease regression
elastogenesis
lysyl oxidase
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020)
期刊论文
MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/11/04
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:
Zhang,Tao
;
Qu,Rong
;
Chan,Shingpan
;
Lai,Mengzhen
;
Tong,Linjiang
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/11/04
Stimuli-activatable nanomaterials for phototherapy of cancer
期刊论文
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 4, 页码: 11
作者:
Zhou, Mengjiao
;
Liu, Xiao
;
Chen, Fangmin
;
Yang, Lili
;
Yuan, Minjian
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2021/06/11
cancer treatment
photodynamic therapy
photothermal therapy
intelligent nanomaterials
stimuli-responsiveness
Role of CD8(+) T lymphocyte cells: Interplay with stromal cells in tumor microenvironment
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1365-1378
作者:
Xie, Qin
;
Ding, Jian
;
Chen, Yi
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/08/17
CD8(+) T lymphocyte
Stromal cell
Tumor microenvironment
Immunosuppression
Immunotherapy
Antitumor
Anti-inflammatory sesquiterpene dimers and diterpenes from the aerial part of Inula japonica
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2021, 页码: 8
作者:
Wu, Rui-Fang
;
Wang, Wen-Qiong
;
Zhou, Bing-Duo
;
Wang, Yi
;
Li, Ya-Ding
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/08/17
Anti-inflammation
composite
ent-kaurane diterpenes
Inula japonica
sesquiterpene dimers
Natural product 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Li, Wen
;
Liao, Li-ping
;
Song, Ning
;
Liu, Yan-jun
;
Ding, Yi-luan
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/06/11
glyceraldehyde 3-phosphate dehydrogenase
1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose
hydrogen deuterium exchange mass spectrometry
reversible inhibitor
glycolysis
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