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浏览/检索结果: 共58条，第1-10条 帮助 限定条件 发表日期：2021    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters 期刊论文 CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256 作者:  Dong, Lei;  Zhang, Min-Yu;  Han, Hai-Hao;  Zang, Yi;  Chen, Guo-Rong 收藏  |  浏览/下载：32/0  |  提交时间：2022/01/18 A simple and effective method for identification of Fraxini Cortex from different sources by multi-mode fingerprint combined with chemometrics 期刊论文 JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 16 作者:  Long, Huali;  Yao, Shuai;  Tian, Wenshuai;  Hou, Jinjun;  Lei, Min 收藏  |  浏览/下载：27/0  |  提交时间：2022/01/18 chemometrics  Fraxini Cortex  high-performance thin-layer chromatography  multi-mode fingerprint  ultra-high-performance liquid chromatography   A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11 作者:  Cheng, Zhiyang;  Huang, Ying;  Shen, Qianqian;  Zhao, Yangrong;  Wang, Lei 收藏  |  浏览/下载：87/0  |  提交时间：2021/11/04 Cancer  beta-glucuronidase  Bioconjugation  Albumin  Camptothecin   Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine 期刊论文 LIFE SCIENCES, 2021, 卷号: 287, 页码: 14 作者:  Xue, Yaru;  Ren, Xuelian;  Zhu, Zhengdan;  Lei, Peng;  Liu, Mengling 收藏  |  浏览/下载：39/0  |  提交时间：2022/01/18 3-n-butylphthalide  Hepatotoxicity  Oxidative stresses  Covalent protein modification  Drug-drug interaction   SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy 期刊论文 JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306 作者:  Huang, Ying;  Wang, Lei;  Cheng, Zhiyang;  Yang, Biyu;  Yu, Jiahui 收藏  |  浏览/下载：24/0  |  提交时间：2021/12/01 Antitumour  Chemotherapy  SN38  Drug delivery systems  Albumin   GADD45 beta stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation 期刊论文 PHARMACOLOGICAL RESEARCH, 2021, 卷号: 173, 页码: 11 作者:  Dong, Yunxia;  Ma, Ningning;  Fan, Lei;  Yuan, Luyang;  Wu, Qian 收藏  |  浏览/下载：61/0  |  提交时间：2021/12/16 Non-alcoholic fatty liver disease  GADD45 beta  HSP72  Lipid accumulation  Insulin resistance   Synthesis of the analogs of plocabulin and their preliminary structure-activity relationship study 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 51, 页码: 5 作者:  Wang, Leiming;  Li, Xin;  Cui, Hong;  Lei, Xinsheng;  Liu, Hongchun 收藏  |  浏览/下载：30/0  |  提交时间：2021/12/01 Marine nature products  Plocabulin  PM060184  Synthesis  Antiproliferation   Two New Cytotoxic Maytansinoids Targeting Tubulin from Trewia nudiflora 期刊论文 PLANTA MEDICA, 2021, 页码: 7 作者:  Lei, Chun;  Li, Ya-Nan;  Li, Jia-Nan;  Zhou, Yu-Bo;  Cui, Ming-Jun 收藏  |  浏览/下载：22/0  |  提交时间：2021/12/16 Trewia nudiflora  Euphorbiaceae  maytansinoids  cytotoxicity  tubulin polymerization   Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090 作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan 收藏  |  浏览/下载：25/0  |  提交时间：2022/01/04 Two New Oleanane-Triterpenoid Saponins from Clinopodium gracile 期刊论文 CHEMISTRY & BIODIVERSITY, 2021, 页码: 8 作者:  Zhao, Ting;  Liu, Yi-Nan;  Sun, Xin-Yu;  Li, Jing-Ya;  Lei, Chun 收藏  |  浏览/下载：18/0  |  提交时间：2021/12/01 Clinopodium gracile  Lamiaceae  triterpenoid saponins  oleanane