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科研机构
上海药物研究所 [20]
内容类型
期刊论文 [20]
发表日期
2021 [20]
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共20条,第1-10条
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发表日期:2021
内容类型:期刊论文
专题:上海药物研究所
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Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence
期刊论文
CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21
作者:
Zan, Gui-Ying
;
Wang, Yu-Jun
;
Li, Xue-Ping
;
Fang, Jun-Fan
;
Yao, Song-Yu
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/12/16
Strategy of De Novo Design toward First-In-Class Imaging Agents for Simultaneously Differentiating Glioma Boundary and Grades
期刊论文
ACS SENSORS, 2021, 卷号: 6, 期号: 9, 页码: 3330-3339
作者:
Yan, Feng
;
Zhuang, Jianfeng
;
Yu, Qian
;
Dou, Zhangqi
;
Jiang, Xuefeng
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
fluorescent probe
bioinformatics analysis
PDGFR beta
glioma imaging
glioma grading
Gut Microbiota in Adipose Tissue Dysfunction Induced Cardiovascular Disease: Role as a Metabolic Organ
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2021, 卷号: 12, 页码: 14
作者:
Yang, Xinyu
;
Zhang, Xianfeng
;
Yang, Wei
;
Yu, Hang
;
He, Qianyan
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/11/04
gut microbiota
adipose tissue dysfunction
molecular endocrinology
cardiovascular disease(s)
gut dysbiosis
Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:
Chen, Zhen-dong
;
Chen, Qian
;
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Zhan, Yan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/04
henagliflozin
food effects
mass balance
pharmacokinetics
SGLT-2 inhibitor
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:
He, Qian
;
Wei, Yuanyuan
;
Liu, Xiao
;
Ye, Rongrong
;
Kong, Linghui
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2021/11/04
BCL9 regulates CD226 and CD96 checkpoints in CD8(+) T cells to improve PD-1 response in cancer
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 14
作者:
Feng, Mei
;
Wu, Zhongen
;
Zhou, Yan
;
Wei, Zhuang
;
Tian, Enming
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  |  
浏览/下载:30/0
  |  
提交时间:2021/11/04
Catalytic System-Controlled Divergent Reaction Strategies for the Construction of Diversified Spiropyrazolone Skeletons from Pyrazolidinones and Diazopyrazolones
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 8
作者:
Fang, Feifei
;
Hu, Shulei
;
Li, Chunpu
;
Wang, Qian
;
Wang, Run
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/11/04
[n+1] annulation
C(sp(3))-H bond activation
N-N bond activation
pyrazolidinones
spiropyrazolones
Detachable Liposomes Combined Immunochemotherapy for Enhanced Triple-Negative Breast Cancer Treatment through Reprogramming of Tumor-Associated Macrophages
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 14, 页码: 6031-6041
作者:
Chen, Mingshu
;
Miao, Yunqiu
;
Qian, Kun
;
Zhou, Xin
;
Guo, Linmiao
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/11/04
Immunochemotherapy
triple-negative breast cancer
liposomes
tumor-associated macrophages
MMP2 response
Iridoid Constituents of Viburnum brachybotryum
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 7, 页码: 1915-1923
作者:
Rao, Li
;
Li, Yao
;
He, Qian
;
Liu, Yu
;
Su, Yu
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/11/04
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