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浏览/检索结果: 共9条，第1-9条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers 期刊论文 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 42, 页码: 18005-18013 作者:  Chai, Xianzhi;  Han, Hai-Hao;  Sedgwick, Adam C.;  Li, Na;  Zang, Yi 收藏  |  浏览/下载：41/0  |  提交时间：2021/05/24 Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10 作者:  Zhang, Xiao-tuan;  Hu, Xiao-bei;  Wang, Han-lin;  Kan, Wei-juan;  Xu, Lei 收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24 DLBCL  BTK inhibitor  ibrutinib resistance  UPR  TUDCA  2-DG   Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11 作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24 In silico screening  Drug design  CBP  Bromodomain  Inhibitor  Acute Myeloblastic Leukemia   Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9 作者:  Han, Jie;  Tian, Yucheng;  Yu, Liang;  Zhang, Qilin;  Xu, Xi 收藏  |  浏览/下载：65/0  |  提交时间：2020/12/24 Ubiquitination  High throughput screening  Drug discovery  USP8   Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors 期刊论文 NATURE, 2020, 页码: 24 作者:  Jin, Zhenming;  Du, Xiaoyu;  Xu, Yechun;  Deng, Yongqiang;  Liu, Meiqin 收藏  |  浏览/下载：44/0  |  提交时间：2020/07/01 Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292 作者:  Zhang, Feng-cai;  Sun, Zhong-ya;  Liao, Li-ping;  Zuo, Yu;  Zhang, Dan 收藏  |  浏览/下载：32/0  |  提交时间：2020/07/01 CBP bromodomain  small-molecule inhibitor  high-throughput screening  TR-FRET  molecular modeling  human leukemia MV4-11 cells   Rapid transport of germ-mimetic nanoparticles with dual conformational polyethylene glycol chains in biological tissues 期刊论文 SCIENCE ADVANCES, 2020, 卷号: 6, 期号: 6, 页码: 16 作者:  Yang, Yiwei;  Tian, Falin;  Nie, Di;  Liu, Yuan;  Qian, Kun 收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01 discoveryofnovelcbpbromodomaininhibitorsthroughtrfretbasedhighthroughputscreening 期刊论文 actapharmacologicasinica, 2020, 卷号: 41, 期号: 2, 页码: 285 作者:  Zhang Fengcai;  Sun Zhongya;  Liao Liping;  Zuo Yu;  Zhang Dan 收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01 CBP bromodomain  small-molecule inhibitor  high-throughput screening  TR-FRET  molecular modeling  human leukemia MV4-11 cells