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科研机构
上海药物研究所 [17]
内容类型
期刊论文 [17]
发表日期
2020 [17]
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共17条,第1-10条
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发表日期:2020
专题:上海药物研究所
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Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
He, Zhi-di
;
Zhang, Meng
;
Wang, Yong-hui
;
He, Yang
;
Wang, Hai-rui
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
tumor-targeted delivery
immunogenic cell death
PD-1
PD-L1 blockade
tumor immune microenvironment
irinotecan
JQ1
immune checkpoint
Co-delivery of all-trans-retinoic acid and doxorubicin for cancer therapy with synergistic inhibition of cancer stem cells (vol 37, pg 405, 2015)
期刊论文
BIOMATERIALS, 2020, 卷号: 263, 页码: 1
作者:
Sun, Rong
;
Liu, Yang
;
Li, Shi-Yong
;
Shen, Song
;
Du, Xiao-Jiao
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2020/12/21
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Pan, Lu-lu
;
Yang, Yong
;
Hui, Min
;
Wang, Shuo
;
Li, Cui-yun
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
forsythin
pharmacokinetics
drug metabolism
drug excretion
sulfation
glucuronidation
organic anion transporter 3
MT1-MMP-Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy
期刊论文
ADVANCED SCIENCE, 2020, 页码: 14
作者:
Wei, Yan
;
Song, Sha
;
Duan, Nianxiu
;
Wang, Feng
;
Wang, Yuxi
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2020/12/24
membrane type 1-matrix metalloproteinase-activated cilengitide
pancreatic cancer
smart liposomes
vascular promotion
Targeted isolation of two disesquiterpenoid macrocephadiolides A and B fromAinsliaea macrocephalausing a molecular networking-based dereplication strategy
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 12, 页码: 1481-1489
作者:
Ren, Yong-Mei
;
Zhou, Shuai-Zhen
;
Zhang, Tian
;
Qian, Meijia
;
Zhang, Rui
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/12/24
Effect of phosphatidylcholine on the stability and lipolysis of nanoemulsion drug delivery systems
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 卷号: 583, 页码: 9
作者:
Zhang, Bo
;
Zhou, Xin
;
Miao, Yunqiu
;
Wang, Xiaoli
;
Yang, Yuting
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/12/24
Phosphatidylcholine
Nanoemulsion
Stability
Lipolysis kinetics
Curcumin
Safety, Clinical Activity, and Pharmacokinetics of Al flutinib (AST2818) in Patients With Advanced NSCLC With EGFR T790M Mutation
期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2020, 卷号: 15, 期号: 6, 页码: 1015-1026
作者:
Shi, Yuankai
;
Zhang, Shucai
;
Hu, Xingsheng
;
Feng, Jifeng
;
Ma, Zhiyong
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/12/24
Alflutinib
NSCLC
EGFR T790M mutation
Efficacy
Safety
Direct C(sp(3))-H acyloxylation of indolin-3-ones with carboxylic acids catalysed by KI
期刊论文
GREEN CHEMISTRY, 2020, 卷号: 22, 期号: 8, 页码: 2354-2358
作者:
Zhao, Yong-Long
;
Tang, Yong-Qin
;
Fei, Xing-Hai
;
Yang, Fen-Fen
;
Cao, Zhuo-Xian
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Smart Tumor Microenvironment-Responsive Nanotheranostic Agent for Effective Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 11
作者:
Guo, Shi-yan
;
Sun, Di
;
Ni, Da-long
;
Yu, Miao-rong
;
Qian, Kun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
hypoxia relief
mesoporous calcium silicate
sequential functions
sustained drug release
synergetic effects
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