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科研机构
上海药物研究所 [12]
内容类型
期刊论文 [12]
发表日期
2020 [12]
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发表日期:2020
专题:上海药物研究所
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Further new complex daphniphyllum alkaloids from the stems and leaves of Daphniphyllum calycinum: Structure and stereochemistry
期刊论文
TETRAHEDRON, 2020, 卷号: 76, 期号: 49, 页码: 8
作者:
Shen, Shou-Mao
;
Li, Heng
;
Wang, Jian-Rong
;
Zeng, Yan-Bo
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
Daphniphyllum calycinum
Daphniphyllum alkaloids
Absolute configuration
Identification of SARS-CoV-2 entry inhibitors among already approved drugs
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:
Yang, Li
;
Pei, Rong-juan
;
Li, Heng
;
Ma, Xin-na
;
Zhou, Yu
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/12/24
COVID-19
SARS-CoV-2
virus entry inhibitors
high throughput screening assay
approved drug library
histamine receptor antagonists
clemastine
SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:
Xia, Zong-jun
;
Ji, Yin-chun
;
Sun, De-qiao
;
Peng, Xia
;
Gao, Ying-lei
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/12/21
ROS1 kinase
ROS1 inhibitor
SAF-189s
lorlatinib
crizotinib resistance
G2032R mutant
NSCLC
The design of a novel near-infrared fluorescent HDAC inhibitor and image of tumor cells
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 17, 页码: 5
作者:
Huang, Ying
;
Ru, Hong-bo
;
Bao, Bin
;
Yu, Jia-hui
;
Li, Jia
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
HDAC
Probe
NIR
Tumor imaging
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
New Steroids from the South China Sea Soft Coral Lobophytum sp.
期刊论文
CHEMISTRY & BIODIVERSITY, 2020, 页码: 6
作者:
Ye, Fei
;
Zhou, Yu-Bo
;
Li, Jia
;
Gu, Yu-Cheng
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
soft coral
Lobophytum
steroids
biological activity
NF-kappa B
Design and synthesis of new lenalidomide analogs via Suzuki cross-coupling reaction
期刊论文
ARCHIV DER PHARMAZIE, 2020, 页码: 10
作者:
Xiao, Donghuai
;
Wang, Yu-jie
;
Wang, Han-lin
;
Zhou, Yu-bo
;
Li, Jia
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
antitumor
arylboronic acid
lenalidomide
Suzuki cross-coupling
A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 11
作者:
Lu, Kang
;
Li, Bo
;
Zhang, Hui
;
Xu, Zhijian
;
Song, Dongliang
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 2, 页码: 804-815
作者:
Zhang, Shu-Wei
;
Gong, Chao-Jun
;
Su, Ming-Bo
;
Chen, Fei
;
He, Ting
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
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