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浏览/检索结果: 共14条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation 期刊论文 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 13 作者:  Guo, An-Di;  Wei, Dan;  Nie, Hui-Jun;  Hu, Hao;  Peng, Chengyuan 收藏  |  浏览/下载：31/0  |  提交时间：2020/12/24 Identification of SARS-CoV-2 entry inhibitors among already approved drugs 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7 作者:  Yang, Li;  Pei, Rong-juan;  Li, Heng;  Ma, Xin-na;  Zhou, Yu 收藏  |  浏览/下载：44/0  |  提交时间：2020/12/24 COVID-19  SARS-CoV-2  virus entry inhibitors  high throughput screening assay  approved drug library  histamine receptor antagonists  clemastine   Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 16, 页码: 6 作者:  Su, Zhicheng;  Yang, Tingyuan;  Wang, Jie;  Lai, Mengzhen;  Tong, Linjiang 收藏  |  浏览/下载：30/0  |  提交时间：2020/12/24 EGFR  NSCLC  C797S   Microbial quantitation of colostrum from healthy breastfeeding women and milk from mastitis patients 期刊论文 ANNALS OF PALLIATIVE MEDICINE, 2020, 卷号: 9, 期号: 4, 页码: 1666-1680 作者:  Tao, Ying-Na;  Tong, Xian-Kun;  Qian, Chen;  Wan, Hua;  Zuo, Jian-Ping 收藏  |  浏览/下载：45/0  |  提交时间：2020/12/24 Colostrum  microbiota  lactational mastitis  breast milk   LOXL1 confers antiapoptosis and promotes gliomagenesis through stabilizing BAG2 期刊论文 CELL DEATH AND DIFFERENTIATION, 2020, 页码: 16 作者:  Yu, Hua;  Ding, Jun;  Zhu, Hongwen;  Jing, Yao;  Zhou, Hu 收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文 MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15 作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang 收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01 Non-small cell lung cancer (NSCLC)  EGFR T790M  Small-molecule inhibitor  Drug resistance  Ack1   2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant 期刊论文 CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287 作者:  Hu, Xianglong;  Xun, Qiuju;  Zhang, Tao;  Zhu, Su-Jie;  Li, Qian 收藏  |  浏览/下载：48/0  |  提交时间：2020/07/01 EGFR(C797S) mutant  SARs  2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidine  Clinical resistance  Fourth-generation inhibitors   An in vitro Fo''rster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10 作者:  Wang, Yu-zhe;  Liu, Xiao;  Way, George;  Madarha, Vipul;  Zhou, Qing-tong 收藏  |  浏览/下载：26/0  |  提交时间：2020/07/01 SUMOylation inhibitor  WNN0605-F008  high-throughput screening  Ubc9  PIAS1  Fo''rster resonance energy transfer  surface plasmon resonance   Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14 作者:  Zhang, Xin;  Xu, Fang;  Tong, Linjiang;  Zhang, Tao;  Xie, Hua 收藏  |  浏览/下载：83/0  |  提交时间：2020/07/01 Epidermal growth factor receptor (EGFR)  Resistance  Proteolysis targeting chimera (PROTAC)  Protein degradation   The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Hao, Bing-bing;  Li, Xiao-jing;  Jia, Xing-long;  Wang, Yu-xing;  Zhai, Lin-hui 收藏  |  浏览/下载：48/0  |  提交时间：2020/07/01 immunomodulatory drugs (IMiDs)  CC-885  BNIP3L  mitophagy  CRBN  acute myeloid leukemia  mitochondria-targeting drugs