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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 发表日期：2020    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12 作者:  Zheng, Yuan-dong;  Zhang, Hua;  Zhan, Yan;  Bian, Yi-cong;  Ma, Sheng 收藏  |  浏览/下载：44/0  |  提交时间：2021/05/24 vicagrel  [C-14]vicagrel  vicagrel pharmacokinetics  vicagrel metabolism  mass balance  P2Y(12) receptor inhibitor   Automated design and optimization of multitarget schizophrenia drug candidates by deep learning 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16 作者:  Tan, Xiaoqin;  Jiang, Xiangrui;  He, Yang;  Zhong, Feisheng;  Li, Xutong 收藏  |  浏览/下载：38/0  |  提交时间：2020/12/21 Schizophrenia  Multitarget antipsychotic drugs  Recurrent neural network  Multitask deep neural network  Automated drug design   Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737 作者:  Li, Xutong;  Li, Zhaojun;  Wu, Xiaolong;  Xiong, Zhaoping;  Yang, Tianbiao 收藏  |  浏览/下载：30/0  |  提交时间：2020/12/21 Deep Learning Enhancing Kinome-Wide Polypharmacology Profiling: Model Construction and Experiment Validation 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 16, 页码: 8723-8737 作者:  Li, Xutong;  Li, Zhaojun;  Wu, Xiaolong;  Xiong, Zhaoping;  Yang, Tianbiao 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/21 Optimizing chemical reaction conditions using deep learning: a case study for the Suzuki-Miyaura cross-coupling reaction 期刊论文 ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 16, 页码: 2269-2277 作者:  Fu, Zunyun;  Li, Xutong;  Wang, Zhaohui;  Li, Zhaojun;  Liu, Xiaohong 收藏  |  浏览/下载：36/0  |  提交时间：2020/12/24 Discovery of triazoloquinoxaline as novel STING agonists via structure-based virtual screening 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 100, 页码: 8 作者:  Hou, Hui;  Yang, Ruirui;  Liu, Xiaohong;  Wu, Xiaolong;  Zhang, Sulin 收藏  |  浏览/下载：3/0  |  提交时间：2020/12/24 Downregulation of TET1 Promotes Bladder Cancer Cell Proliferation and Invasion by Reducing DNA Hydroxymethylation of AJAP1 期刊论文 FRONTIERS IN ONCOLOGY, 2020, 卷号: 10, 页码: 16 作者:  Yan, Yi-lin;  Huang, Zheng-nan;  Zhu, Zhen;  Cui, Yang-yan;  Li, Mei-qian 收藏  |  浏览/下载：86/0  |  提交时间：2020/12/24 ten-eleven translocation 1 (TET1)  DNA methylation  bladder cancer  vitamin C  adherens junction-associated protein 1 (AJAP1)   A rapid and convenient derivatization method for quantitation of short-chain fatty acids in human feces by ultra-performance liquid chromatography/tandem mass spectrometry 期刊论文 RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2020, 卷号: 34, 期号: 9, 页码: 11 作者:  Fu, Huan;  Zhang, Qing-li;  Huang, Xiao-wu;  Ma, Zheng-hua;  Zheng, Xiao-li 收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01 Synthesis and biological investigation of triazolopyridinone derivatives as potential multireceptor atypical antipsychotics 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 8, 页码: 6 作者:  Shi, Wenqiang;  Wang, Yu;  Wu, Chunhui;  Yang, Feipu;  Zheng, Wei 收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Triazolopyridinone  Antipsychotic  Multireceptor  5-HT1A receptor   Loss of hnRNP A1 in murine skeletal muscle exacerbates high-fat diet-induced onset of insulin resistance and hepatic steatosis 期刊论文 JOURNAL OF MOLECULAR CELL BIOLOGY, 2020, 卷号: 12, 期号: 4, 页码: 277-290 作者:  Zhao, Mingxia;  Shen, Lihong;  Ouyang, Zijun;  Li, Manru;  Deng, Guoliang 收藏  |  浏览/下载：23/0  |  提交时间：2020/12/24 hnRNP A1  insulin resistance  hepatic steatosis  glycogen synthesis