CORC

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CORC

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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01
Exploring binding mechanisms of VEGFR2 with three drugs lenvatinib, sorafenib, and sunitinib by molecular dynamics simulation and free energy calculation 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 5, 页码: 934-948
作者:  Wang, Yu;  Peng, Cheng;  Wang, Guimin;  Xu, Zhijian;  Luo, Yongfeng
收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01
Improving the accuracy of predicting protein-ligand binding-free energy with semiempirical quantum chemistry charge 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 4, 页码: 303-321
作者:  Peng, Cheng;  Wang, Jinan;  Yu, Yuqi;  Wang, Guimin;  Chen, Zhaoqiang
收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01
Crack suppression in additively manufactured tungsten by introducing secondary-phase nanoparticles into the matrix 期刊论文
INTERNATIONAL JOURNAL OF REFRACTORY METALS & HARD MATERIALS, 2019, 卷号: 79, 期号: 无, 页码: 158-163
作者:  Li, Kailun;  Wang, Dianzheng;  Xing, Leilei;  Wang, Yafei;  Yu, Chenfan
收藏  |  浏览/下载：51/0  |  提交时间：2020/03/31
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载：137/0  |  提交时间：2019/06/28
Optimal Revascularization Threshold of Fractional Flow Reserve and its Effect on Outcomes: Perspectives From a High-Volume Center in China 期刊论文
ANGIOLOGY, 2019, 卷号: 70, 期号: 5
作者:  Du, Yu;  Yang, Bangguo;  Zhang, Jianwei;  Liu, Wei;  Wang, Zhijian
收藏  |  浏览/下载：33/0  |  提交时间：2019/12/04
Linezolid Consumption Facilitates the Development of Linezolid Resistance in Enterococcus faecalis in a Tertiary-Care Hospital: A 5-Year Surveillance Study 期刊论文
MICROBIAL DRUG RESISTANCE, 2019, 卷号: 25, 期号: 6
作者:  Bai, Bing;  Hu, Kaitao;  Zeng, Jun;  Yao, Weiming;  Li, Duoyun
收藏  |  浏览/下载：16/0  |  提交时间：2019/12/05
Staphylococcus aureus with an erm-mediated constitutive macrolide-lincosamide-streptogramin B resistance phenotype has reduced susceptibility to the new ketolide, solithromycin 期刊论文
BMC INFECTIOUS DISEASES, 2019, 卷号: 19
作者:  Yao, Weiming;  Xu, Guangjian;  Li, Duoyun;  Bai, Bing;  Wang, Hongyan
收藏  |  浏览/下载：26/0  |  提交时间：2019/12/05
Large electrocaloric effect over a wide temperature range in BaTiO3-modified lead-free ceramics 期刊论文
JOURNAL OF MATERIALS CHEMISTRY C, 2019, 卷号: 7, 页码: 1353-1358
作者:  Zhao, Luo;  Ke, Xiaoqin;  Zhou, Zhijian;  Liao, Xiaoqi;  Li, Junjie
收藏  |  浏览/下载：14/0  |  提交时间：2019/11/19
Environment friendly chemical mechanical polishing of copper 期刊论文
APPLIED SURFACE SCIENCE, 2019, 卷号: 467, 页码: 5-11
作者:  Zhang, Zhenyu;  Cui, Junfeng;  Zhang, Jiabo;  Liu, Dongdong;  Yu, Zhijian
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/02
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