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科研机构
大连理工大学 [12]
山东大学 [10]
海洋研究所 [7]
北京航空航天大学 [4]
南京地理与湖泊研究所 [3]
成都中医药大学 [3]
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期刊论文 [54]
会议论文 [2]
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2019 [56]
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发表日期:2019
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Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:
Xu, Qi
;
Wu, Ning
;
Li, Xiangqian
;
Guo, Chuanlong
;
Li, Chao
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/03/20
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
作者:
Wang, Lijun
;
Guo, Chuanlong
;
Li, Xiuxue
;
Yu, Xuemin
;
Li, Xiangqian
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  |  
浏览/下载:187/0
  |  
提交时间:2019/08/29
Bromophenol-thiazolylhydrazone hybrids
Synthesis
Multifunctional agents
eIF4E/eIF4G interaction
Autophagy
ROS
Chalcone-analogue fluorescent probes for detecting thiophenols in seawater samples
期刊论文
TALANTA, 2019, 卷号: 201, 页码: 301-308
作者:
Liu, Hua
;
Guo, Chuanlong
;
Guo, Shuju
;
Fan, Junting
;
Wang, Lijun
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  |  
浏览/下载:80/0
  |  
提交时间:2019/08/29
Fluorescent probe
Thiophenol
Seawater sample
Chalcone
BOS-93, a novel bromophenol derivative, induces apoptosis and autophagy in human A549 lung cancer cells via PI3K/Akt/mTOR and MAPK signaling pathway
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2019, 卷号: 17, 期号: 5, 页码: 3848-3858
作者:
Guo, Chuanlong
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  |  
浏览/下载:119/0
  |  
提交时间:2019/08/28
bromophenol
apoptosis
autophagy
phosphoinositide 3-kinase
protein kinase B
mechanistic target of rapamycin signaling
reactive oxygen species
Discovery of Novel Bromophenol Thiosemicarbazone Hybrids as Potent Selective Inhibitors of Poly(ADP-ribose) Polymerase-1 (PARP-1) for Use in Cancer
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3051-3067
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Li, Xinxue
;
Wang, Shuaiyu
;
Yu, Xuemin
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  |  
浏览/下载:79/0
  |  
提交时间:2019/08/28
Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185
作者:
Li, Xiangqian
;
Xu, Qi
;
Li, Chao
;
Luo, Jiao
;
Li, Xiuxue
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  |  
浏览/下载:60/0
  |  
提交时间:2019/05/15
Anti-diabetic
PTP1B inhibitor
Selectivity
BKS db mice
Toxicity
Design and Synthesis of a Fluorescent Probe with a Large Stokes Shift for Detecting Thiophenols and Its Application in Water Samples and Living Cells
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 2, 页码: 14
作者:
Liu, Hua
;
Guo, Chuanlong
;
Guo, Shuju
;
Wang, Lijun
;
Shi, Dayong
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  |  
浏览/下载:54/0
  |  
提交时间:2019/08/27
fluorescent probe
thiophenol
water samples
chalcone
living cells
Cell-intrinsic PD-1 promotes proliferation in pancreatic cancer by targeting CYR61/CTGF via the hippo pathway
期刊论文
CANCER LETTERS, 2019, 卷号: 460
作者:
Pu, Ning
;
Gao, Shanshan
;
Yin, Hanlin
;
Li, Jian-ang
;
Wu, Wenchuan
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  |  
浏览/下载:41/0
  |  
提交时间:2019/12/05
Pancreatic ductal adenocarcinoma
Programmed cell death protein-1
Immune checkpoint
Hippo signaling
Nomogram
Enrichment of shortmutant cell-free DNA fragments enhanced detection of pancreatic cancer
期刊论文
EBIOMEDICINE, 2019, 卷号: 41
作者:
Liu, Xiaoyu
;
Liu, Lingxiao
;
Ji, Yuan
;
Li, Changyu
;
Wei, Tao
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  |  
浏览/下载:24/0
  |  
提交时间:2019/12/05
Pancreatic cancer
Cell-free DNA
Fragmentation
Tissue biopsy
Diagnosis and prognosis
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