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中国医学科学院 北... [19]
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期刊论文 [177]
会议论文 [1]
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2018 [178]
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Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation
Effect of Micro-scale Y Addition on the Fracture Properties of Al–Cu–Mn Alloy
期刊论文
Chinese Journal of Mechanical Engineering (English Edition), 2018, 卷号: 31, 期号: 1
作者:
Guo, Ting-Biao
;
Zhang, Feng
;
Ding, Wan-Wu
;
Jia, Zhi
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  |  
浏览/下载:0/0
  |  
提交时间:2020/11/14
Aluminum metallography
Brittleness
Copper alloys
Copper metallography
Deterioration
Ductile fracture
Fracture toughness
Grain boundaries
Hardness
Heat treatment
Manganese alloys
Mechanical properties
Microstructure
Plasticity
Rare earths
Scanning electron microscopy
Solid solutions
Spectrometers
Ternary alloys
Yttrium metallography
Artificial aging treatments
Deformation compatibility
Energy dispersive spectrometers
Fracture characteristics
Inter-metallic compounds
Microstructure and mechanical properties
Optical microscopes
Strengthening effect
Effect of Micro-scale Y Addition on the Fracture Properties of Al-Cu-Mn Alloy
期刊论文
CHINESE JOURNAL OF MECHANICAL ENGINEERING, 2018, 卷号: 31, 期号: 1
作者:
Guo, Ting-Biao
;
Zhang, Feng
;
Ding, Wan-Wu
;
Jia, Zhi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/11/15
Al-Cu-Mn alloy
Solid solution
Fracture toughness
Mechanical properties
The impact of biomass burning on total suspended particulate matter in the southeastern Tibetan Plateau
期刊论文
ATMOSPHERIC ENVIRONMENT, 2018, 卷号: 193, 页码: 33-39
作者:
Zhang, NN (Zhang, Ning-Ning)[ 1 ]
;
Wang, QY (Wang, Qi-Yuan)[ 1 ]
;
Su, XL (Su, Xiao-Li)[ 1 ]
;
Zhang, T (Zhang, Ting)[ 1 ]
;
Tao, J (Tao, Jun)[ 2 ]
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  |  
浏览/下载:94/0
  |  
提交时间:2018/11/21
Levoglucosan
Biomass burning
Tibetan plateau
The impact of biomass burning on total suspended particulate matter in the southeastern Tibetan Plateau
期刊论文
ATMOSPHERIC ENVIRONMENT, 2018, 卷号: 193, 页码: 33-39
作者:
Zhu, CS (Zhu, Chong-Shu)[ 1 ]
;
Zhang, NN (Zhang, Ning-Ning)[ 1 ]
;
Wang, QY (Wang, Qi-Yuan)[ 1 ]
;
Su, XL (Su, Xiao-Li)[ 1 ]
;
Zhang, T (Zhang, Ting)[ 1 ]
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2018/11/21
Levoglucosan
Biomass Burning
Tibetan Plateau
Cytotoxic sesquiterpenoids from the leaves of Magnolia grandiflora
期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 155, 页码: 182-190
作者:
Ding, Lin-Fen
;
Su, Jia
;
Pan, Zheng-Hong
;
Zhang, Zhi-Jun
;
Li, Xiao-Nian
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  |  
浏览/下载:46/0
  |  
提交时间:2018/11/12
Magnolia Grandiflora (Magnoliaceae)
Sesquiterpenoids
Cytotoxic Activity
Nf-kappa b Transcriptional Activity
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors
期刊论文
Bioorganic chemistry, 2018, 卷号: 83, 页码: 277-288
作者:
Cheng, Zhi-Qiang
;
Zhu, Kong-Kai
;
Zhang, Juan
;
Song, Jia-Li
;
Muehlmann, Luis Alexandre
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
Internalization of the pseudorabies virus via macropinocytosis analyzed by quantum dot-based single-virus tracking
期刊论文
Chemical communications, 2018, 卷号: 54, 期号: 79, 页码: 11184-11187
作者:
Lv, Cheng
;
Lin, Yi
;
Sun, En-Ze
;
Tang, Bo
;
Ao, Jian
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/05/08
Hydrological response of biological soil crusts to global warming: A ten-year simulative study
期刊论文
GLOBAL CHANGE BIOLOGY, 2018, 卷号: 24, 期号: 10, 页码: 4960-4971
作者:
Li, Xin-Rong
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  |  
浏览/下载:55/0
  |  
提交时间:2019/10/09
biological soil crusts
dew entrapment
evaporation
infiltration
open-top chamber
warming and reduced precipitation
Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632
作者:
Zhang, Mei
;
Xie, Zhi-fu
;
Zhang, Run-tao
;
Chen, Da-kai
;
Gu, Min
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
non-alcoholic fatty liver disease
AMP-activated protein kinase
AMPK activator
homogeneous time-resolved fluorescence
metabolic disorders
ob/ob mice
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