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北京航空航天大学 [166]
高能物理研究所 [57]
复旦大学上海医学院 [28]
武汉大学 [19]
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西安交通大学 [11]
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期刊论文 [419]
其他 [4]
会议论文 [3]
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2018 [426]
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Organic Ch... [2]
地球科学::地理学 [1]
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Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:
Liu, Xuesong
;
Wang, Beilei
;
Chen, Cheng
;
Jiang, Zongru
;
Hu, Chen
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/11
ABL kinase
Kinase inhibitor
ABL mutant
CML
March3 attenuates il-1 beta-triggered inflammation by mediating k48-linked polyubiquitination and degradation of il-1ri
期刊论文
Proceedings of the national academy of sciences of the united states of america, 2018, 卷号: 115, 期号: 49, 页码: 12483-12488
作者:
Lin, Heng
;
Gao, Deng
;
Hu, Ming-Ming
;
Zhang, Man
;
Wu, Xiao-Xia
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  |  
浏览/下载:111/0
  |  
提交时间:2019/05/08
March3
Il-1
Listeria monocytogenes
Polyubiquitination
Inflammation
Site-Specific N-Glycan Characterization of Grass Carp Serum IgM
期刊论文
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9, 页码: 16
作者:
Geng, Hui
;
Zhang, Yong-An
;
Xiong, Li
;
Wan, Cui-Hong
;
Cui, Yan-Fang
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  |  
浏览/下载:96/0
  |  
提交时间:2018/12/29
teleost
grass carp
imrnunoglobulin M
N-glycan
liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS)
glycosylation
matrix assisted laser desorption/ionization-time-offlight-MS (MALDI-TOF-MS)
Enhanced triacylglycerol production in the diatom Phaeodactylum tricornutum by inactivation of a Hotdog-fold thioesterase gene using TALEN-based targeted mutagenesis
期刊论文
BIOTECHNOLOGY FOR BIOFUELS, 2018, 卷号: 11, 期号: 1, 页码: 18
作者:
Hao, Xiahui
;
Luo, Ling
;
Jouhet, Juliette
;
Rebeille, Fabrice
;
Marechal, Eric
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  |  
浏览/下载:68/0
  |  
提交时间:2019/07/01
Acyl-CoA thioesterase
Acyl-CoA
Fatty acids
Phaeodactylum tricornutum
TALEN
Triacylglycerols
Design of the poloidal field system for KTX
期刊论文
PLASMA SCIENCE & TECHNOLOGY, 2018, 卷号: 20, 期号: 11, 页码: 9
作者:
You, Wei
;
Li, Hong
;
Mao, Wenzhe
;
Bai, Wei
;
Tu, Cui
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  |  
浏览/下载:39/0
  |  
提交时间:2019/12/11
RFP
KTX
poloidal field system
electromagnetic design
Premnafulvol A: A Diterpenoid with a 6/5/7/3-Fused Tetracyclic Core and Its Biosynthetically Related Analogues from Premna fulva
期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 19, 页码: 6314-6317
作者:
Pu, De-Bing
;
Du, Bao-Wen
;
Chen, Wen
;
Gao, Jun-Bo
;
Hu, Kun
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  |  
浏览/下载:40/0
  |  
提交时间:2018/11/12
Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
作者:
Wang, Beilei
;
Wu, Jiaxin
;
Wu, Yun
;
Chen, Cheng
;
Zou, Fengming
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  |  
浏览/下载:69/0
  |  
提交时间:2019/12/25
CDK9
Kinase inhibitor
Structure-activity relationship
Leukemia
Sema3E/PlexinD1 inhibition is a therapeutic strategy for improving cerebral perfusion and restoring functional loss after stroke in aged rats
期刊论文
NEUROBIOLOGY OF AGING, 2018, 卷号: 70, 页码: 102-116
作者:
Yue, Zhen-Yu
;
Zhou, Yi-Fan
;
Li, Peng-Cheng
;
Wu, Jie-Hong
;
Haslam, James Andrew
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2018/12/29
Ischemic stroke
Cerebral perfusion
Functional neovascularization
BBB integrity
Endothelial cells
Pericytes
SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA
期刊论文
PLOS PATHOGENS, 2018, 卷号: 14, 期号: 10, 页码: 17
作者:
Wei, Jin
;
Lian, Huan
;
Guo, Wei
;
Chen, Yun-Da
;
Zhang, Xia-Nan
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2018/12/29
Sema3E/PlexinD1 inhibition is a therapeutic strategy for improving cerebral perfusion and restoring functional loss after stroke in aged rats
期刊论文
NEUROBIOLOGY OF AGING, 2018, 卷号: 70, 页码: 102-116
作者:
Zhou, Yi-Fan
;
Li, Peng-Cheng
;
Wu, Jie-Hong
;
Haslam, James Andrew
;
Mao, Ling
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2018/11/05
Ischemic Stroke
Cerebral Perfusion
Functional Neovascularization
Bbb Integrity
Endothelial Cells
Pericytes
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