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Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation
Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations
期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298
作者:
Zhu, Kongkai
;
Tao, Hongrui
;
Song, Jia-Li
;
Jin, Lu
;
Zhang, Yuanyuan
收藏
  |  
浏览/下载:130/0
  |  
提交时间:2019/01/08
PRMT5 inhibitor
Arginine methylation
Virtual screening
Molecular docking
Molecular dynamics simulation
Middle Jurassic-Early Cretaceous tectonic evolution of the Bayanhushuo area, southern Great Xing'an Range, NE China: constraints from zircon U-Pb geochronological and geochemical data of volcanic and subvolcanic rocks
期刊论文
INTERNATIONAL GEOLOGY REVIEW, 2018, 卷号: 60, 期号: 15, 页码: 1883-1905
作者:
Guan, Qing-Bin
;
Liu, Zheng-Hong
;
Wang, Bin
;
Wang, Xiong
;
Wang, Xing-An
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/08/27
Middle Jurassic-Early Cretaceous
Southern Great Xing'an Range
volcanic rocks
Mongol-Okhotsk Ocean
zircon U-Pb geochronology
geochemistry
Middle Jurassic-Early Cretaceous tectonic evolution of the Bayanhushuo area, southern Great Xing'an Range, NE China: constraints from zircon U-Pb geochronological and geochemical data of volcanic and subvolcanic rocks
期刊论文
INTERNATIONAL GEOLOGY REVIEW, 2018, 卷号: 60, 期号: 15, 页码: 1883-1905
作者:
Guan, Qing-Bin
;
Liu, Zheng-Hong
;
Wang, Bin
;
Wang, Xiong
;
Wang, Xing-An
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2018/12/21
Middle Jurassic-Early Cretaceous
Southern Great Xing'an Range
volcanic rocks
Mongol-Okhotsk Ocean
zircon U-Pb geochronology
geochemistry
Divergence and plasticity shape adaptive potential of the Pacific oyster
期刊论文
NATURE ECOLOGY & EVOLUTION, 2018, 卷号: 2, 期号: 11, 页码: 1751-1760
作者:
Li, Li
;
Li, Ao
;
Song, Kai
;
Meng, Jie
;
Guo, Ximing
收藏
  |  
浏览/下载:172/0
  |  
提交时间:2019/05/15
Development of a primary culture system for haematopoietic tissue cells from Cherax quadricarinatus and an exploration of transfection methods
期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2018, 卷号: 88, 页码: 45-54
作者:
Xu, Xiaohui
;
Duan, Hu
;
Shi, Yingli
;
Xie, Shijun
;
Song, Zhan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/08/27
Cherax quadricarinatus
Culture of haematopoietic tissue cells
Transfection
WSSV infection
Divergence and plasticity shape adaptive potential of the Pacific oyster
期刊论文
NATURE ECOLOGY & EVOLUTION, 2018, 卷号: 2, 期号: 11, 页码: 1751-1760
作者:
Li, Li
;
Li, Ao
;
Song, Kai
;
Meng, Jie
;
Guo, Ximing
收藏
  |  
浏览/下载:192/0
  |  
提交时间:2018/12/21
Cross Cultural Validation and Extension of the Clinical Assessment Interview for Negative Symptoms (CAINS) in the Chinese Context: Evidence from a Spectrum Perspective
期刊论文
SCHIZOPHRENIA BULLETIN, 2018, 卷号: 44, 页码: S547-S555
作者:
Xie, Dong-jie
;
Shi, Hai-song
;
Lui, Simon S. Y.
;
Shi, Chuan
;
Li, Ying
收藏
  |  
浏览/下载:211/0
  |  
提交时间:2018/11/24
Negative Symptoms
Schizotypy
Schizophre Nia Spectrum Disorders
Low-pleasure beliefs in patientswith schizophrenia and individuals with social anhedonia
期刊论文
SCHIZOPHRENIA RESEARCH, 2018, 卷号: 201, 页码: 137-144
作者:
Yang, Yin
;
Yang, Zhuo-ya
;
Zou, Ying-min
;
Shi, Hai-song
;
Wang, Yi
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2018/12/13
Anhedonia
Low-pleasure Beliefs
Schizophrenia
Beliefs About Pleasure Scale
Experience Of Pleasure
Cytotoxic sesquiterpenoids from the leaves of Magnolia grandiflora
期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 155, 页码: 182-190
作者:
Ding, Lin-Fen
;
Su, Jia
;
Pan, Zheng-Hong
;
Zhang, Zhi-Jun
;
Li, Xiao-Nian
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2018/11/12
Magnolia Grandiflora (Magnoliaceae)
Sesquiterpenoids
Cytotoxic Activity
Nf-kappa b Transcriptional Activity
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