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浏览/检索结果: 共34条，第1-10条 帮助 限定条件 发表日期：2018    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Ainsliatriolides A and B, Two Guaianolide Trimers from Ainsliaea fragrans and Their Cytotoxic Activities 期刊论文 JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 22, 页码: 14175-14180 作者:  Zhang, Rui;  Tang, Chunping;  Liu, Hong-Chun;  Ren, Yongmei;  Xu, Cheng-hui 收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 21, 页码: 9621-9636 作者:  Peng, Panfeng;  Chen, Huan;  Zhu, Ya;  Wang, Zhilong;  Li, Jian 收藏  |  浏览/下载：57/0  |  提交时间：2019/01/08 Asymmetric Synthesis of the C15-C32 Fragment of Alotamide and Determination of the Relative Stereochemistry 期刊论文 MARINE DRUGS, 2018, 卷号: 16, 期号: 11 作者:  Shi, Hao-yun;  Xie, Yang;  Hu, Pei;  Guo, Zi-qiong;  Lu, Yi-hong 收藏  |  浏览/下载：69/0  |  提交时间：2019/01/08 alotamide  asymmetric synthesis  relative structural determination   Synthesis of androgen receptor antagonists containing a pentafluorosulfanyl (SF5) moiety 期刊论文 ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 11 作者:  Jin, Jiyu;  Zhou, Yan;  Yang, Dehua;  Zhang, Qiumeng;  Wang, Ming-Wei 收藏  |  浏览/下载：76/0  |  提交时间：2019/01/08 androgen receptor  antagonist  enzalutamide  pentafluorosulfanyl   Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y(1) receptor antagonists 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 302-310 作者:  Peng, Jingjing;  Zhao, Lifen;  Wang, Lanlan;  Chen, Hui;  Qiu, Yunguang 收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08 P2Y(1) receptor antagonist  2-(phenoxyaryl)-3-urea derivatives  Anti-Platelet   Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719 作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia 收藏  |  浏览/下载：90/0  |  提交时间：2019/01/08 Anticancer drug  Phosphatidylinositol 3-kinase  Structure-activity relationship   Dictyoptesterols A-C, Delta(22)-24-oxo cholestane-type sterols with potent PTP1B inhibitory activity from the brown alga Dictyopteris undulata Holmes 期刊论文 FITOTERAPIA, 2018, 卷号: 130, 页码: 241-246 作者:  Yang, Fei;  Zhang, Liang-Wei;  Feng, Mei-Tang;  Liu, Ai-Hong;  Li, Jia 收藏  |  浏览/下载：55/0  |  提交时间：2019/01/08 Dictyotaceae  Dictyopteris undulate  Cholestane-type sterols  Dictyoptesterols A-C  Protein tyrosine phosphatase-1B inhibitors   Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632 作者:  Zhang, Mei;  Xie, Zhi-fu;  Zhang, Run-tao;  Chen, Da-kai;  Gu, Min 收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08 non-alcoholic fatty liver disease  AMP-activated protein kinase  AMPK activator  homogeneous time-resolved fluorescence  metabolic disorders  ob/ob mice   Artemisinin analogue SM934 ameliorates DSS-induced mouse ulcerative colitis via suppressing neutrophils and macrophages 期刊论文 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1633-1644 作者:  Yan, Yu-xi;  Shao, Mei-juan;  Qi, Qing;  Xu, Yan-sheng;  Yang, Xiao-qian 收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08 SM934  artemisinin analogue  ulcerative colitis  inflammatory bowel disease (IBD)  neutrophils macrophage  NF-kappa B  RAW 2647 cells  THP-1-derived macrophages   Three New Cytotoxic Monoterpenoid Bisindole Alkaloids from Tabernaemontana bufalina 期刊论文 PLANTA MEDICA, 2018, 卷号: 84, 期号: 15, 页码: 1127-1133 作者:  Zhou, Si-Yuan;  Zhou, Ting-Lan;  Qiu, Guofu;  Huan, Xiajuan;  Miao, Ze-Hong 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 Tabernaemontana bufalina  Apocynaceae  monoterpenoid indole alkaloids  cytotoxicity