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CORC

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Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 20, 页码: 8407-8424
作者:  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Wu, Hong;  Qi, Ziping
收藏  |  浏览/下载：47/0  |  提交时间：2019/06/17
Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 期号: 无, 页码: 674-697
作者:  Chen, Yongfei;  Wu, Jiaxin;  Wang, Aoli;  Qi, Ziping;  Jiang, Taoshan
收藏  |  浏览/下载：778/0  |  提交时间：2018/08/17
Structure-activity relationship investigation for benzonaphthyridinone derivatives as novel potent Bruton's tyrosine kinase (BTK) irreversible inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 545-557
作者:  Wang, Beilei;  Deng, Yuanxin;  Chen, Yongfei;  Yu, Kailin;  Wang, Aoli
收藏  |  浏览/下载：44/0  |  提交时间：2018/08/16
Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl) phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 131, 页码: 107-125
作者:  Liang, Qianmao;  Chen, Yongfei;  Yu, Kailin;  Chen, Cheng;  Zhang, Shouxiang
收藏  |  浏览/下载：40/0  |  提交时间：2018/07/26
Discovery of 2-((3-Acrylamido-4-methylphenyl)amino)-N-(2-methyl5-(3,4,5-trimethoxybenzamido)phenyI)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-BMX-078) as a Highly Potent and Selective Type II Irreversible Bone Marrow Kinase in the X Chromosome (BMX) Kinase Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 5, 页码: 1793-1816
作者:  Liang, Xiaofei;  Lv, Fengchao;  Wang, Beilei;  Yu, Kailin;  Wu, Hong
收藏  |  浏览/下载：800/0  |  提交时间：2018/07/04
Discovery of 4-Methyl-N-(44(4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((1-nicotinoylpiperidin-4-y1)oxy)benzamide (CHMFL-ABL/KIT-155) as a Novel Highly Potent Type II ABL/KIT Dual Kinase Inhibitor with a Distinct Hinge Binding 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 1, 页码: 273-289
作者:  Wang, Qiang;  Liu, Feiyang;  Wang, Beilei;  Zou, Fengming;  Qi, Ziping
收藏  |  浏览/下载：30/0  |  提交时间：2018/07/04
Chinese water-pipe tobacco smoking acts as a risk factor for inflammation and endothelial dysfunction 期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2017, 卷号: 10, 期号: 4
作者:  Dai, Yuxiang;  Dong, Lubing;  Li, Gang;  Qin, Shaoxi;  Wang, Zhenquan
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/05
Assembling hierarchical metal-oxygen building units with a semirigid tetracarboxylate ligand into a three-dimensional framework for nitrobenzene sensing 期刊论文
DALTON TRANSACTIONS, 2017, 卷号: 46, 页码: 6523-6527
作者:  Song, Xue-Zhi;  Gao, Li-Guo;  Wang, Yu-Xiang;  Chen, Xiao-Lei;  Qiao, Liang
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/02
TOUSE: A Fair User Selection Mechanism Based on Dynamic Time Warping for MU-MIMO Networks 期刊论文
KSII TRANSACTIONS ON INTERNET AND INFORMATION SYSTEMS, 2017, 卷号: 11, 页码: 4398-4417
作者:  Tang, Zhaoshu;  Qin, Zhenquan;  Zhu, Ming;  Fang, Jian;  Wang, Lei
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03
BELIA: Bandwidth estimate-based link increase algorithm for MPTCP 期刊论文
IET Networks, 2017, 卷号: 6, 页码: 94-101
作者:  Zhu, Ming;  Wang, Lei;  Qin, Zhenquan;  Ding, Nan;  Fang, Jian
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/03

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