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科研机构
上海药物研究所 [5]
内容类型
期刊论文 [5]
发表日期
2017 [5]
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发表日期:2017
专题:上海药物研究所
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Anti-proliferation activity of terpenoids isolated from Euphorbia kansui in human cancer cells and their structure-activity relationship
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 10, 页码: 766-774
作者:
Hou Jin-Jun
;
Shen Yao
;
Yang Zhou
;
Fang Lin
;
Cai Lu-Ying
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Terpenoids
Anti-proliferation activity
Human cancer cells
Structure-activity relationship
Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf(V600E) inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1059-1068
作者:
Wang, Gui-min
;
Wang, Xiang
;
Zhu, Jian-ming
;
Guo, Bin-bin
;
Yang, Zhuo
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
B-Raf(V600E) inhibitor
anticancer
vemurafenib
deazapurine
fragment reassembly
molecular docking
structure-activity relationship
W2476 ameliorates beta-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1024-1037
作者:
Li, Ting
;
Lin, Guang-yao
;
Zhong, Li
;
Zhou, Yan
;
Wang, Jia
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
diabetes
glucose
TXNIP
beta-cells
W2476
high-throughput screening
(5R)-5-hydroxytriptolide ameliorates lupus nephritis in MRL/lpr mice by preventing infiltration of immune cells
期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2017, 卷号: 312, 期号: 4, 页码: F769-F777
作者:
Zhang, Lu-yao
;
Li, Heng
;
Wu, Yan-wei
;
Cheng, Lei
;
Yan, Yu-xi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
systemic lupus erythematosus
inflammation
chemokines
An enhanced targeted identification strategy for the selective identification of flavonoid O-glycosides from Carthamus tinctorius by integrating offline two-dimensional liquid chromatography/linear ion-trap-Orbitrap mass spectrometry, high-resolution diagnostic product ions/neutral loss filtering and liquid chromatography-solid phase extraction-nuclear magnetic resonance
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2017, 卷号: 1491, 页码: 87-97
作者:
Yao, Chang-liang
;
Yang, Wen-zhi
;
Si, Wei
;
Shen, Yao
;
Zhang, Nai-xia
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Enhanced targeted identification strategy
Offline two-dimensional liquid
chromatography
Diagnostic product ions filtering
Liquid chromatography-solid phase
extraction-nuclear magnetic resonance
Carthamus tinctorius
Flavonoid O-glycoside
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