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浏览/检索结果: 共10条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Curvularin derivatives from the soil-derived fungus Aspergillus polyporicola PSU-RSPG187 期刊论文 PHYTOCHEMISTRY LETTERS, 2017, 卷号: 22, 页码: 122-127 作者:  Choochuay, Jutatip;  Xu, Xin;  Rukachaisirikul, Vatcharin;  Guedduaythong, Piyada;  Phongpaichit, Souwalak 收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 Aspergillus polyporicola  Cytochalasins  Curvularins  Soil-derived fungi  Antimicrobial activity  Cytotoxic activity   Cytosporone derivatives from the endophytic fungus Phomopsis sp PSU-H188 期刊论文 PHYTOCHEMISTRY LETTERS, 2017, 卷号: 22, 页码: 219-223 作者:  Kongprapan, Thippaya;  Xu, Xin;  Rukachaisirikul, Vatcharin;  Phongpaichit, Souwalak;  Sakayaroj, Jariya 收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 Phomopsis sp.  Hevea brasiliensis  Cytosporone  Antibacterial activity  Cytotoxic activity  Glucose output inhibitory activity  Protection of pancreatic beta-cells   Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 页码: 128-152 作者:  Wang, Zhengyu;  Shi, Xiaofan;  Zhang, Huan;  Yu, Liang;  Cheng, Yanhua 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Type 2 diabetes mellitus  Hypoglycemia  Dyslipidemia  Glucokinase activators  N-Thiazol-2-yl-benzamides   DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway 期刊论文 JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169 作者:  Zhou, Ting-Ting;  Ma, Fei;  Shi, Xiao-Fan;  Xu, Xin;  Du, Te 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Gaq signaling  hepatic gluconeogenesis  protein kinase B (AKT)  type 2 diabetes mellitus (T2DM)   Design and optimization of purine derivatives as in vivo active PDE10A inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 13, 页码: 3315-3329 作者:  Chen, Liu;  Chen, Danqi;  Tang, Le;  Ren, Jing;  Chen, Jiaojiao 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Phosphodiesterase  PDE10A  Purine  Inhibitor  Anti-psychotic   Discovery and Biological Evaluation of a Series of Pyrrolo[2,3-b]pyrazines as Novel FGFR Inhibitors 期刊论文 MOLECULES, 2017, 卷号: 22, 期号: 4 作者:  Zhang, Yan;  Liu, Hongchun;  Zhang, Zhen;  Wang, Ruifeng;  Liu, Tongchao 收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 FGFR1  inhibitor  kinase inhibitor  pyrazine  hinge binder   Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 4, 页码: 551-560 作者:  Sun, Jing-ya;  Wang, Ji-dong;  Wang, Xin;  Liu, Hong-chun;  Zhang, Min-min 收藏  |  浏览/下载：45/0  |  提交时间：2019/01/08 HDAC  chromopeptide A  FK228  human prostate cancer  cell cycle arrest  apoptosis  cancer cell migration  PC3 xenograft model   The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent kappa-Opioid Agonistic Activities 期刊论文 ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 4, 页码: 766-776 作者:  Li, Wei;  Long, Jian-Dong;  Qian, Yuan-Yuan;  Long, Yu;  Xu, Xue-Jun 收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 kappa-opioid receptor  mu-opioid receptor  nepenthones  4,5-epoxymorphinans  pharmacological heterogeneity  structure activity relationship  binding structure   Synthesis and glucose-stimulate insulin secretion (GSIS) evaluation of vindoline derivatives 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 5, 页码: 1316-1318 作者:  Xiao, Chengqian;  Tian, Yunan;  Lei, Min;  Chen, Fanglei;  Gan, Xianwen 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Vindoline  Natural product  Glucose-stimulate insulin secretion (GSIS)  Structure-activity relationships (SARs)   c-Myc Alteration Determines the Therapeutic Response to FGFR Inhibitors 期刊论文 CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 期号: 4, 页码: 974-984 作者:  Liu, Hongyan;  Ai, Jing;  Shen, Aijun;  Chen, Yi;  Wang, Xinyi 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08