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浏览/检索结果: 共32条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1673-1682 作者:  Liu, Shi-en;  Hu, Jun-chi;  Zhang, Hao;  Xu, Pan;  Wan, Wei 收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 phosphoglycerate mutase 1 (PGAM1)  human cancers  metabolic target  C-terminal region  conformational changes  molecular dynamics simulation   First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans 期刊论文 ARCHIVES OF TOXICOLOGY, 2017, 卷号: 91, 期号: 12, 页码: 3913-3925 作者:  Yang, Mengbi;  Ruan, Jianqing;  Gao, Hong;  Li, Na;  Ma, Jiang 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Pyrrolizidine alkaloid N-oxide  Pyrrolizidine alkaloid  Hepatic sinusoidal obstruction syndrome  Pyrrole-protein adduct  Biotransformation  Toxicokinetic   Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues 期刊论文 ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 44, 页码: 9352-9361 作者:  Jiang, Hao;  Xing, Jing;  Wang, Chen;  Zhang, Hao;  Yue, Liyan 收藏  |  浏览/下载：111/0  |  提交时间：2019/01/08 PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KII alpha, Inhibits the Growth of Breast Cancer Cells 期刊论文 CANCER RESEARCH, 2017, 卷号: 77, 期号: 22, 页码: 6253-6266 作者:  Li, Jiangmei;  Gao, Zhen;  Zhao, Dan;  Zhang, Lunfeng;  Qiao, Xinhua 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464 作者:  Zhou, Shengbin;  Duan, Yanan;  Wang, Jiang;  Zhang, Jin;  Sun, Haifeng 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Tetrahydroberberine  4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines  Mitochondrial respiration  AMPK indirect activators  db/db mice   Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 8888-8905 作者:  Wang, Chen;  Jiang, Hao;  Jin, Jia;  Xie, Yiqian;  Chen, Zhifeng 收藏  |  浏览/下载：116/0  |  提交时间：2019/01/08 Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532 作者:  Chen, Wen-hua;  Song, Shan-shan;  Qi, Ming-hui;  Huan, Xia-juan;  Wang, Ying-qing 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors   Catalytic and catalyst-free diboration of alkynes 期刊论文 ORGANIC CHEMISTRY FRONTIERS, 2017, 卷号: 4, 期号: 11, 页码: 2235-2255 作者:  Zhao, Fei;  Jia, Xiuwen;  Li, Pinyi;  Zhao, Jingwei;  Zhou, Yu 收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 Adduct ion-targeted qualitative and quantitative analysis of polyoxypregnanes by ultra-high pressure liquid chromatography coupled with triple quadrupole mass spectrometry 期刊论文 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2017, 卷号: 145, 页码: 127-136 作者:  Wu, X.;  Zhu, Lin;  Ma, Jiang;  Ye, Yang;  Lin, Ge 收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Adduct ion formation  Marsdenia tenacissima  Polyoxypregnane  Triple quadrupole mass spectrometry   Aspirin Inhibits Cancer Metastasis and Angiogenesis via Targeting Heparanase 期刊论文 CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 期号: 20, 页码: 6267-6278 作者:  Dai, Xiaoyang;  Yan, Juan;  Fu, Xuhong;  Pan, Qiuming;  Sun, Danni 收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08