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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors 期刊论文 FRONTIERS IN CHEMISTRY, 2017, 卷号: 5 作者:  Hu, Xiuqin;  Wang, Disha;  Tong, Yi;  Tong, Linjiang;  Wang, Xia 收藏  |  浏览/下载：62/0  |  提交时间：2019/01/08 EGFR  tyrosine kinase inhibitors  anilinopyrtmidine  glycosides  carbohydrate-based drugs   Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527 作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang 收藏  |  浏览/下载：57/0  |  提交时间：2019/01/08 Epidermal growth factor receptor  Tyrosine kinase inhibitors  Non-small cell lung cancer  T790M  Mutant-selective   Chemical constituents from hypoglycemic active part of Plantaginis Semen 期刊论文 Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, 卷号: 42, 期号: 21, 页码: 4150-4153 作者:  Peng, Qing-Hua;  Han, Zhu-Zhen;  Tong, Ren-Chao;  Hu, Xin-Quan;  Yang, Qi-Ming 收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 C-H Trifluoromethylation of 2-Substituted/Unsubstituted Aminonaphthoquinones at Room Temperature with Bench-Stable (CF3SO2)(2)Zn: Synthesis and Antiproliferative Evaluation 期刊论文 JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 82, 期号: 13, 页码: 6795-6800 作者:  Li, Jing;  Zhang, Xiaofei;  Xiang, Haoyue;  Tong, Linjiang;  Feng, Fang 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 A structure-guided optimization of pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of EGFR(L858R/T790M) mutant with improved pharmacokinetic properties 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 126, 页码: 1107-1117 作者:  Yu, Lei;  Huang, Minhao;  Xu, Tianfeng;  Tong, Linjiang;  Yan, Xiao-e 收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 EGFR(T790M) mutant  Pyrido[2,3-d]pyrimidin-7-ones  Pharmacokinetic property  NSCLC  Irreversible inhibitor   Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution 期刊论文 ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 4156-4168 作者:  He, Jin-Xue;  Wang, Meng;  Huan, Xia-Juan;  Chen, Chuan-Huizi;  Song, Shan-Shan 收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 MPH  PARP inhibitor  homologous recombination  antitumor activity  synthetic lethality