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浏览/检索结果: 共20条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5332-5336 作者:  Fu, Yan;  Tang, Shuai;  Su, Yi;  Lan, Xiaojing;  Ye, Yan 收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Cyclin-dependent kinase  CDK inhibitor  Structure-activity relationship  In vitro and in vivo profiling   Supramolecular assembly of fluorogenic glyco-dots from perylenediimide-based glycoclusters for targeted imaging of cancer cells 期刊论文 CHEMICAL COMMUNICATIONS, 2017, 卷号: 53, 期号: 87, 页码: 11937-11940 作者:  Liu, Ying;  Ji, Ding-Kun;  Dong, Lei;  Galanos, Nicolas;  Zang, Yi 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 Evaluation of in vitro and in vivo activity of a multityrosine kinase inhibitor, AL3810, against human thyroid cancer 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1533-1542 作者:  Xie, Qin;  Chen, Hui;  Ai, Jing;  Gao, Ying-lei;  Geng, Mei-yu 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 thyroid cancer  AL3810  multi-tyrosine kinases inhibitor  angiogenesis  RET   Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   Soluble epoxide hydrolase activation by S-nitrosation contributes to cardiac ischemia-reperfusion injury 期刊论文 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2017, 卷号: 110, 页码: 70-79 作者:  Ding, Yuzhu;  Li, Yazi;  Zhang, Xu;  He, Jinlong;  Lu, Dong 收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 Epoxyeicosatrienoic acid  Ischemia-reperfusion  Nitric oxide  S-nitrosation  Soluble epoxide hydrolase   Heteromers of ae opioid and dopamine D1 receptorsmodulate opioid-induced locomotor sensitization in a dopamine-independent manner 期刊论文 BRITISH JOURNAL OF PHARMACOLOGY, 2017, 卷号: 174, 期号: 17, 页码: 2842-2861 作者:  Tao, Yi-Min;  Yu, Chuan;  Wang, Wei-Sheng;  Hou, Yuan-Yuan;  Xu, Xue-Jun 收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin 期刊论文 NATURE COMMUNICATIONS, 2017, 卷号: 8 作者:  Wang, Ya-fang;  Zhang, Jie;  Su, Yi;  Shen, Yan-yan;  Jiang, Dong-xian 收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1038-1047 作者:  Yang, Zhong-min;  Liao, Xue-mei;  Chen, Yi;  Shen, Yan-yan;  Yang, Xin-ying 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 homologous recombination repair defects  breast cancer  ovarian cancer  TALEN  combined biomarker  simmiparib  olaparib   Polymeric Immunoglobulin Receptor Promotes Tumor Growth in Hepatocellular Carcinoma 期刊论文 HEPATOLOGY, 2017, 卷号: 65, 期号: 6, 页码: 1948-1962 作者:  Yue, Xihua 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Oral Bioavailability and Mass Balance Studies of a Novel Anti-arrhythmic Agent Sulcardine Sulfate in Sprague-Dawley Rats and Beagle Dogs 期刊论文 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2017, 卷号: 42, 期号: 3, 页码: 453-459 作者:  Lu, You-li;  Li, Shui-jun;  Liu, Gang-yi;  Li, Xiao-chuan;  Yang, Ding 收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08