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科研机构
上海药物研究所 [6]
暨南大学 [1]
内容类型
期刊论文 [7]
发表日期
2016 [7]
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发表日期:2016
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Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective alpha(1A)-Adrenoceptor Antagonists
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 20, 页码: 9489-9502
作者:
Guo, Diliang
;
Li, Jing
;
Lin, Henry
;
Zhou, Yu
;
Chen, Ying
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 14, 页码: 6772-6790
作者:
Li, Shiliang
;
Xu, Hongling
;
Cui, Shichao
;
Wu, Fangshu
;
Zhang, Youli
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Enzyme-Dependent [4+2] Cycloaddition Depends on Lid-like Interaction of the N-Terminal Sequence with the Catalytic Core in PyrI4
期刊论文
CELL CHEMICAL BIOLOGY, 2016, 卷号: 23, 期号: 3, 页码: 352-360
作者:
Zheng, Qingfei
;
Guo, Yujiao
;
Yang, Linlin
;
Zhao, Zhixiong
;
Wu, Zhuhua
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
Dual Physically Cross-Linked Double Network Hydrogels with High Mechanical Strength, Fatigue Resistance, Notch-Insensitivity, and Self-Healing Properties
期刊论文
2016, 卷号: 8, 期号: [db:dc_citation_issue], 页码: 34034
作者:
Yuan, Ningxiao[1]
;
Xu, Lu[1]
;
Wang, Hualiang[1]
;
Fu, Youpeng[1]
;
Zhang, Zhe[1]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase
期刊论文
ACTA PHARMACEUTICA SINICA B, 2016, 卷号: 6, 期号: 1, 页码: 32-45
作者:
Zhou, Yu
;
Liu, Jun
;
Zheng, Mingyue
;
Zheng, Shuli
;
Jiang, Chunyi
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
5-Lipoxygenase
5-LOX inhibitors
Pyrazole derivatives
Leukotrienes-related diseases
In vivo
Benzo-fuse heterocyle
Ischemic incults
Brain inflammation
structuraloptimizationandbiologicalevaluationofl5disubstitutedpyrazole3carboxaminesaspotentinhibitorsofhuman5lipoxygenase
期刊论文
actapharmaceuticasinicab, 2016, 卷号: 6, 期号: 1, 页码: 32
作者:
Zhou Yu
;
Liu Jun
;
Zheng Mingyue
;
Zheng Shuli
;
Jiang Chunyi
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
5-Lipoxygenase
5-LOX inhibitors
Pyrazole derivatives
Leukotrienes-related diseases
In vivo
Benzo-fused heterocycle
Ischemic incults
Brain inflammation
Structural optimization and biological evaluation of l,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase
期刊论文
Acta Pharmaceutica Sinica B, 2016, 卷号: 6, 期号: 1, 页码: 32
作者:
Zhou Yu
;
Liu Jun
;
Zheng Mingyue
;
Zheng Shuli
;
Jiang Chunyi
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/12/24
5-Lipoxygenase
5-LOX inhibitors
Pyrazole derivatives
Leukotrienes-related diseases
In vivo
Benzo-fused heterocycle
Ischemic incults
Brain inflammation
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