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Discovery of N-((1-(4-(3-(3-((6,7-Dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) as a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I "Gatekeeper" Mutant of cKIT Kinase 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 18, 页码: 8456-8472
作者:  Li, Binhua;  Wang, Aoli;  Liu, Juan;  Qi, Ziping;  Liu, Xiaochuan
收藏  |  浏览/下载:42/0  |  提交时间:2017/11/21
Molecular mechanism of z alpha 1-antitrypsin deficiency 期刊论文
Journal of biological chemistry, 2016, 卷号: 291, 期号: 30, 页码: 15674-15686
作者:  Huang, Xin;  Zheng, Ying;  Zhang, Fei;  Wei, Zhenquan;  Wang, Yugang
收藏  |  浏览/下载:20/0  |  提交时间:2019/05/09
Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML) 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 29, 页码: 45562-45574
作者:  Liu, Feiyang;  Wang, Beilei;  Wang, Qiang;  Qi, Ziping;  Chen, Cheng
收藏  |  浏览/下载:40/0  |  提交时间:2017/11/21
Discovery of N-(34(1-lsonicotinoylpiperidin-4-yl)oxy)-4methylpheny1)-3-(trifluoromethyl)benzamide (CHMFL-KIT-110) as a Selective, Potent, and Orally Available Type II c-KIT Kinase Inhibitor for Gastrointestinal Stromal Tumors (GISTs) 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 8, 页码: 3964-3979
作者:  Wang, Qang;  Liu, Feiyang;  Wang, Beilei;  Zou, Fengming;  Chen, Cheng
收藏  |  浏览/下载:15/0  |  提交时间:2017/11/10
Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 5, 页码: 1984-2004
作者:  Liang, Xiaofei;  Liu, Xiaochuan;  Wang, Beilei;  Zou, Fengming;  Wang, Aoli
收藏  |  浏览/下载:46/0  |  提交时间:2017/11/06
Optimized periodical charging in large-scale deployed WSNs 会议论文
58th IEEE Global Communications Conference, GLOBECOM 2015, San Diego, CA, United states, December 6, 2015 - December 10, 2015
作者:  Qin, Zhenquan;  Lu, Bingxian;  Zhou, Chunting;  Wang, Lei;  Zhu, Ming
收藏  |  浏览/下载:3/0  |  提交时间:2017/01/20
Characteristics of mud diapirs and mud volcanoes and their relationship to oil and gas migration and accumulation in a marginal basin of the northern South China Sea 期刊论文
Environmental Earth Sciences, 2016, 卷号: 75, 期号: 15, 页码: 1112
作者:  He, Jiaxiong;  Wang, Shuhong;  Zhang, Wei;  Yan, Wen;  Lu, Zhenquan
收藏  |  浏览/下载:14/0  |  提交时间:2017/07/12
Tectono-thermal evolution and gas source potential for natural gas hydrates in the Qilian Mountain permafrost, China 期刊论文
2016, 卷号: 36, 页码: 32-41
作者:  Zuo, Yinhui;  Wang, Quanfeng;  Lu, Zhenquan;  Chen, Hui
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/04
Voltage Stability of Multiple Distributed Generators in Distribution Networks 会议论文
作者:  Wang, Andi;  Liu, Chongxin;  Gueguen, Herve;  Sun, Zhenquan
收藏  |  浏览/下载:2/0  |  提交时间:2019/11/26
Characteristics of mud diapirs and mud volcanoes and their relationship to oil and gas migration and accumulation in a marginal basin of the northern South China Sea 期刊论文
ENVIRONMENTAL EARTH SCIENCES, 2016, 卷号: 75, 期号: 15, 页码: 1122
作者:  He, Jiaxiong;  Wang, Shuhong;  Zhang, Wei;  Yan, Wen;  Lu, Zhenquan
收藏  |  浏览/下载:39/0  |  提交时间:2016/12/22


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