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浏览/检索结果: 共14条，第1-10条 帮助 限定条件 发表日期：2016    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Targeting Hsp90 with FS-108 circumvents gefitinib resistance in EGFR mutant non-small cell lung cancer cells 期刊论文 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 12, 页码: 1587-1596 作者:  Wang, Yue-qin;  Shen, Ai-jun;  Sun, Jing-ya;  Wang, Xin;  Liu, Hong-chun 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 non-small cell lung cancer  gefitinib resistance  Hsp90   Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 124, 页码: 981-991 作者:  Ma, Guang-Hui;  Ye, Yan;  Zhang, Dan;  Xu, Xin;  Si, Pei 收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 HFMD  EV71 3C(Pro)  Non-peptidyl inhibitor  Virtual screening   beta-Resorcylic macrolide and octahydronaphthalene derivatives from a seagrass-derived fungus Fusarium sp PSU-ES123 期刊论文 TETRAHEDRON, 2016, 卷号: 72, 期号: 41, 页码: 6421-6427 作者:  Saetang, Praphatsorn;  Rukachaisirikul, Vatcharin;  Phongpaichit, Souwalak;  Sakayaroj, Jariya;  Shi, Xiaofan 收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 beta-Resorcylic macrolide  Octahydronaphthalene derivative  Antifungal activity  Cytotoxic activity  Protection of pancreatic beta-cells   Design, Synthesis and Biological Evaluation of 6-(2,6-Dichloro-3,5-dimethoxyphenyl)-4-substituted-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors 期刊论文 MOLECULES, 2016, 卷号: 21, 期号: 10 作者:  Zhang, Zhen;  Zhao, Dongmei;  Dai, Yang;  Cheng, Maosheng;  Geng, Meiyu 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 cancer  FGFR  inhibitor  4-substituted-1H-indazole   Design and synthesis of benzylpiperidine inhibitors targeting the menin-MLL1 interface 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 18, 页码: 4472-4476 作者:  Ren, Jing;  Xu, Wei;  Tang, Le;  Su, Minbo;  Chen, Danqi 收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Menin  Mixed lineage leukemia  MLL1  SAR  Inhibitor   NMR-based platform for fragment-based lead discovery used in screening BRD4-targeted compounds 期刊论文 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 7, 页码: 984-993 作者:  Yu, Jun-lan;  Chen, Tian-tian;  Zhou, Chen;  Lian, Fu-lin;  Tang, Xu-long 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 fragment-based lead discovery  NMR  bromodomain  BRD4 inhibitors   Development of Heat Shock Protein (Hsp90) Inhibitors To Combat Resistance to Tyrosine Kinase Inhibitors through Hsp90-Kinase Interactions 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 12, 页码: 5563-5586 作者:  Wang, Meining;  Shen, Aijun;  Zhang, Chi;  Song, Zilan;  Ai, Jing 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities 期刊论文 ONCOTARGET, 2016, 卷号: 7, 期号: 25, 页码: 38091-38104 作者:  Wang, Ying;  Zhan, Zhengsheng;  Jiang, Xifei;  Peng, Xia;  Shen, Yanyan 收藏  |  浏览/下载：54/0  |  提交时间：2019/01/08 c-Met  kinase inhibitor  Simm530   Design and synthesis of novel benzo[d]oxazol-2(3H)-one derivatives bearing 7-substituted-4-enthoxyquinoline moieties as c-Met kinase inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 115, 页码: 191-200 作者:  Lu, Dong;  Shen, Aijun;  Liu, Yang;  Peng, Xia;  Xing, Weiqiang 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 c-Met  Benzo[d]oxazol-2(3H)-one-quinolone  Molecular hybridization  Anti-cancer   Formation of 1,3-diazocine by palladium catalyzed C-H arylation 期刊论文 TETRAHEDRON LETTERS, 2016, 卷号: 57, 期号: 21, 页码: 2311-2314 作者:  Tang, Le;  Ren, Jing;  Ma, Yuchi;  Wang, Xin;  Chen, Lin 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 1,3-Diazocine  C-H arylation  8-Aminoimidazo[1,2-alpha]pyrazines  8-Membered ring  Groebke-Blackburn-Bienayme reaction