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Promyelocytic leukemia protein induces arsenic trioxide resistance through regulation of aldehyde dehydrogenase 3 family member A1 in hepatocellular carcinoma 期刊论文
Cancer Letters, 2015, 卷号: 366, 期号: 1, 页码: 112-122
作者:  Zhang, Xin;  Yang, Xin-Rong;  Sun, Chao;  Hu, Bo;  Sun, Yun-Fan
收藏  |  浏览/下载:14/0  |  提交时间:2019/12/03
HCC  hepatocellular carcinoma  ATO  arsenic trioxide  APL  acute promyelocytic leukemia  PML  promyelocytic leukemia protein  RARα  retinoic acid receptor α  ALDH3A1  aldehyde dehydrogenase 3 family member A1  qRT-PCR  quantitative real-time reverse transcriptase polymerase chain reaction  TMA  tissue microarray  OS  overall survival  TTR  time to recurrence  DMEM  Dulbecco's modified Eagle's medium  CB7  1-[(4-fluorophenyl) sulfonyl]-2-methyl-1H-benzimidazole  siRNA  small interfering RNA  shRNA  small hairpin RNA  GFP  green fluorescent protein  MTT  3-(4,5-dimethylthiazol2-yl)-2,5-diphenyltetrazolium bromide  ChIP  chromatin immunoprecipitation  ORF  open reading frame  ROS  reactive oxygen species  DCFH-DA  2,7-dichlorfluorescein-diacetate  AFP  α-fetoprotein  ALT  alanine aminotransferase  TTP  time to progression  GO  gene ontology  NFκB  nuclear factor kappa-light-chain-enhancer of activated B cells  Bcl-2  B-cell lymphoma 2  Promyelocytic leukemia protein  Aldehyde dehydrogenase 3 family member A1  Reactive oxygen species  Tumor growth  Drug resistance  


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