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CORC

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Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin 期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2022, 卷号: 30
作者:  Zhang, Lin;  Li, Ling;  Wang, Xia;  Liu, Huimin;  Zhang, Yibin
收藏  |  浏览/下载：24/0  |  提交时间：2022/12/23
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:  Li, Haobin;  Cai, Maohua;  Cao, Fei;  Yu, Dehua;  Yang, Jing
收藏  |  浏览/下载：14/0  |  提交时间：2022/12/22
Gut microbiota: An emerging therapeutic approach of herbal medicine for prevention of colorectal cancer 期刊论文
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, 卷号: 12
作者:  Ying, Hua-Zhong;  Xie, Wei;  Wang, Meng-Chuan;  He, Jia-Qi;  Zhang, Huan-Huan
收藏  |  浏览/下载：17/0  |  提交时间：2022/12/23
Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng
收藏  |  浏览/下载：19/0  |  提交时间：2022/12/23
An overview of kinase downregulators and recent advances in discovery approaches 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Wang, Beilei;  Wu, Hong;  Hu, Chen;  Wang, Haizhen;  Liu, Jing
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/25
Protein degradation technology: a strategic paradigm shift in drug discovery 期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 卷号: 14
作者:  Li, Haobin;  Dong, Jinyun;  Cai, Maohua;  Xu, Zhiyuan;  Cheng, Xiang-Dong
收藏  |  浏览/下载：31/0  |  提交时间：2021/11/01
Recent Update on Development of Small-Molecule STAT3 Inhibitors for Cancer Therapy: From Phosphorylation Inhibition to Protein Degradation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:  Dong, Jinyun;  Cheng, Xiang-Dong;  Zhang, Wei-Dong;  Qin, Jiang-Jiang
收藏  |  浏览/下载：14/0  |  提交时间：2021/08/31
Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118
作者:  Zhou, Xiaoting;  Gao, Yan;  Wang, Weiwei;  Yang, Xiaolin;  Yang, Xiuna
收藏  |  浏览/下载：53/0  |  提交时间：2021/06/15
Discovery of a highly potent and selective Bruton's tyrosine kinase inhibitor avoiding impairment of ADCC effects for B-cell non-Hodgkin lymphoma 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5
作者:  Liu, Juan;  Liang, Qianmao;  Wang, Aoli;  Zou, Fengming;  Qi, Ziping
收藏  |  浏览/下载：18/0  |  提交时间：2020/11/30
Chemical protein synthesis-assisted high-throughput screening strategies for D-peptides in drug discovery 期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31
作者:  Li, Ying;  Cao, Xiuxiu;  Tian, Changlin;  Zheng, Ji-Shen
收藏  |  浏览/下载：21/0  |  提交时间：2020/12/07

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