QQ客服 官方微博 反馈留言

浏览/检索结果: 共11条，第1-10条 帮助 限定条件 专题：合肥物质科学研究院    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract 期刊论文 CANCER COMMUNICATIONS, 2022 作者:  Wu, Huanwen;  Yu, Zicheng;  Liu, Yueping;  Guo, Lei;  Teng, Lianghong 收藏  |  浏览/下载：28/0  |  提交时间：2022/12/22 Neuroendocrine carcinomas  Gastrointestinal tract  Genomic characterization  Heterogeneity  Therapeutic implications   A photochemically covalent lock stabilizes aptamer conformation and strengthens its performance for biomedicine 期刊论文 NUCLEIC ACIDS RESEARCH, 2022 作者:  Zhou, Fang;  Wang, Peng;  Chen, Jianghuai;  Zhu, Zhijia;  Li, Youshan 收藏  |  浏览/下载：22/0  |  提交时间：2022/12/23 Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文 FRONTIERS IN CHEMISTRY, 2022, 卷号: 10 作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng 收藏  |  浏览/下载：24/0  |  提交时间：2022/12/23 targeted protein degradation  PROTAC  molecular glue  chemically induced proximity  drug discovery and development   Epigallocatechin gallate-loaded tetrahedral DNA nanostructures as a novel inner ear drug delivery system 期刊论文 NANOSCALE, 2022, 卷号: 14 作者:  Chen, Yuming;  Gu, Jiayi;  Liu, Yan;  Xu, Ke;  Song, Jie 收藏  |  浏览/下载：19/0  |  提交时间：2022/12/23 SPARCL1 exhibits different expressions in left- and right-sided colon cancer and is downregulated via DNA methylation 期刊论文 EPIGENOMICS, 2021 作者:  Hu, Hanguang;  Wu, Dehao;  Liu, Xibo;  Yu, Haifeng;  Xu, Junxi 收藏  |  浏览/下载：78/0  |  提交时间：2021/11/01 DNA methylation  left-sided colon cancer  metastasis  right-sided colon cancer  SPARCL1   CircURI1 interacts with hnRNPM to inhibit metastasis by modulating alternative splicing in gastric cancer 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118 作者:  Wang, Xiaolin;  Li, Jingxin;  Bian, Xing;  Wu, Cheng;  Hua, Jinghan 收藏  |  浏览/下载：58/0  |  提交时间：2021/09/06 circURI1  cancer  metastasis  hnRNPM  splicing   METTL3-induced UCK2 m(6)A hypermethylation promotes melanoma cancer cell metastasis via the WNT/beta-catenin pathway 期刊论文 ANNALS OF TRANSLATIONAL MEDICINE, 2021 作者:  Wu, Hao;  Xu, Haochao;  Jia, Dongdong;  Li, Tao;  Xia, Liming 收藏  |  浏览/下载：42/0  |  提交时间：2021/08/30 Uridine-cytidine kinase 2 (UCK2)  database  m(6)A  metastasis  melanoma cancer   FK228 sensitizes radioresistant small cell lung cancer cells to radiation 期刊论文 CLINICAL EPIGENETICS, 2021, 卷号: 13 作者:  Li, Hong;  Ma, Liying;  Bian, Xing;  Lv, Yang;  Lin, Wenchu 收藏  |  浏览/下载：50/0  |  提交时间：2021/04/26 Small cell lung cancer  FK228  Histone deacetylase  PI3K  Radioresistance  DNA damage repair   Combined Metabolomic Analysis of Plasma and Tissue Reveals a Prognostic Risk Score System and Metabolic Dysregulation in Esophageal Squamous Cell Carcinoma 期刊论文 FRONTIERS IN ONCOLOGY, 2020, 卷号: 10 作者:  Chen, Zhongjian;  Dai, Yalan;  Huang, Xiancong;  Chen, Keke;  Gao, Yun 收藏  |  浏览/下载：59/0  |  提交时间：2020/11/30 esophageal squamous cell carcinoma (ESCC)  metabolomics  risk score  prognosis  diagnosis  indoleamine 2  3-dioxygenase 1 (IDO1)  artificial intelligence   Electrostatic interactions determine entrance/release order of substrates in the catalytic cycle of adenylate kinase 期刊论文 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2019, 卷号: 87, 期号: 4, 页码: 337-347 作者:  Ye, Chun;  Ding, Chengtao;  Ma, Rongsheng;  Wang, Junfeng;  Zhang, Zhiyong 收藏  |  浏览/下载：9/0  |  提交时间：2020/07/14 conformational transition  domain motion  enhanced sampling  molecular dynamics simulation  protein dynamics