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中国医学科学院 北... [11]
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期刊论文 [11]
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2018 [4]
2017 [1]
2016 [1]
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专题:中国医学科学院 北京协和医学院
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Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
Adipocyte-specific DKO of Lkb1 and mTOR protects mice against HFD-induced obesity, but results in insulin resistance
期刊论文
2018, 卷号: 59, 期号: 6, 页码: 974-981
作者:
Xiong, Yan
;
Xu, Ziye
;
Wang, Yizhen
;
Kuang, Shihuan
;
Shan, Tizhong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
adipose
metabolism
liver kinase B1
mammalian target of rapamycin
Co-targeting PLK1 and mTOR induces synergistic inhibitory effects against esophageal squamous cell carcinoma
期刊论文
2018, 卷号: 96, 期号: 8, 页码: 807-817
作者:
Liu, Ting-Ting
;
Yang, Kai-Xia
;
Yu, Jing
;
Cao, Ying-Ya
;
Ren, Jian-Song
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Esophageal cancer
Polo-like kinase 1
Mammalian/mechanistic target of rapamycin
BI 2536
Rapamycin
The mTOR Kinase Inhibitor CZ415 Inhibits Human Papillary Thyroid Carcinoma Cell Growth
期刊论文
2018, 卷号: 46, 期号: 2, 页码: 579-590
作者:
Li, Xiaobin
;
Li, Zongze
;
Song, Yimin
;
Liu, Wenjing
;
Liu, Ziwen
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Papillary thyroid carcinoma (PTC)
MTOR
CZ415
Autophagy
Peripheral Neuropathy and Hindlimb Paralysis in a Mouse Model of Adipocyte-Specific Knockout of Lkb1
期刊论文
2017, 卷号: 24, 页码: 127-136
作者:
Xiong, Yan
;
Page, Jessica C.
;
Narayanan, Naagarajan
;
Wang, Chao
;
Jia, Zhihao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Brown adipocyte
Liver kinase b1 (serine/threonine kinase 11)
Inflammation
Sciatic nerve
mTOR
Paralysis
Will targeting PI3K/Akt/mTOR signaling work in hematopoietic malignancies?
期刊论文
2016, 卷号: 3, 页码: 31
作者:
Gao Yanan
;
Yuan Chase Y
;
Yuan Weiping
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
Phosphatidylinositol 3-kinase (PI3K)
genetic analysis
hematological malignancies
mammalian target of rapamycin (mTOR)
protein kinase B (Akt)
Inhibition of Notch Signaling Promotes the Adipogenic Differentiation of Mesenchymal Stem Cells Through Autophagy Activation and PTEN-PI3K/AKT/mTOR Pathway
期刊论文
2015, 卷号: 36, 期号: 5, 页码: 1991-2002
作者:
Song, Bao-quan
;
Chi, Ying
;
Li, Xue
;
Du, Wen-jing
;
Han, Zhi-Bo
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/13
Notch signaling
Mesenchymal stem cells
Adipogenesis
Autophagy
Phosphoinositide 3-kinase
Akt
mTOR
Mechanistic perspectives of calorie restriction on vascular homeostasis
期刊论文
2014, 卷号: 57, 期号: 8, 页码: 742-754
作者:
Liu Yue
;
Chen HouZao
;
Liu DePei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/13
calorie restriction (CR)
vascular homeostasis
Sirtuin 1 (SIRT1)
AMP-activated protein kinase (AMPK)
mammalian target of rapamycin (mTOR)
endothelial nitric oxide synthase (eNOS)
PDK4 Protein Promotes Tumorigenesis through Activation of cAMP-response Element-binding Protein (CREB)-Ras Homolog Enriched in Brain (RHEB)-mTORC1 Signaling Cascade
期刊论文
2014, 卷号: 289, 期号: 43, 页码: 29739-29749
作者:
Liu, Zhibo
;
Chen, Xinxin
;
Wang, Ying
;
Peng, Haiyong
;
Wang, Yanan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/13
cAMP-response Element-binding Protein (CREB)
Cellular Regulation
DNA-Protein Interaction
Mechanistic Target of Rapamycin (mTOR)
Warburg Effect
Ras Homolog Enriched in Brain
Pyruvate Dehydrogenase Kinase 4
Signaling
Tumorigenesis
FLZ PROTECTS DOPAMINERGIC NEURON THROUGH ACTIVATING PROTEIN KINASE B/MAMMALIAN TARGET OF RAPAMYCIN PATHWAY AND INHIBITING RTP801 EXPRESSION IN PARKINSON'S DISEASE MODELS
期刊论文
2012, 卷号: 202, 页码: 396-404
作者:
Bao, X.Q.
;
Kong, X.C.
;
Qian, C.
;
Zhang, D.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/13
Parkinson's disease
FLZ
tyrosine hydroxylase
Akt
mTOR
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