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科研机构
中国医学科学院 北... [17]
内容类型
期刊论文 [16]
会议论文 [1]
发表日期
2019 [2]
2018 [6]
2017 [8]
2013 [1]
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专题:中国医学科学院 北京协和医学院
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Efficacy and Safety of Gefitinib as Third-line Treatment in NSCLC Patients With Activating EGFR Mutations Treated With First-line Gefitinib Followed by Second-line Chemotherapy A Single-Arm, Prospective, Multicenter Phase II Study (RE-CHALLENGE,
期刊论文
2019, 卷号: 42, 期号: 5, 页码: 432-439
作者:
Song, Yong
;
Wu, Yi-Long
;
Cao, Le-Jie
;
Chen, Jian-Hua
;
Ma, Zhi-Yong
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/01/03
re-challenge
gefitinib
T790M mutation
progression-free survival
EGFR-TKI
NSCLC
Successful treatment with osimertinib and its subsequent resistance mechanism in a patient with non-small-cell lung cancer harboring acquired EGFR T790M mutation after recovery from AC0010-induced interstitial lung disease
期刊论文
2019, 卷号: 12, 页码: 5545-5549
作者:
Wang, Hanping
;
Zhang, Li
;
Shi, Xiaohua
;
Zhang, Xiaotong
;
Si, Xiaoyan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/01/03
osimertinib
AC0010
interstitial lung disease
resistance mechanism
transformation
large-cell neuroendocrine carcinoma
Re-biopsy status among Chinese non-small-cell lung cancer patients who progressed after icotinib therapy
期刊论文
2018, 卷号: 11, 页码: 7513-7519
作者:
Wang, Hanping
;
Zhang, Li
;
Si, Xiaoyan
;
Zhang, Xiaotong
;
Wang, Mengzhao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
re-biopsy
T790M mutation
resistant mechanism
EGFR-TKI
icotinib
non-small-cell lung cancer
Penetration of the blood-brain barrier by avitinib and its control of intra/extra-cranial disease in non-small cell lung cancer harboring the T790M mutation
期刊论文
2018, 卷号: 122, 页码: 1-6
作者:
Wang Hanping
;
Zhang Li
;
Hu Pei
;
Zheng Xin
;
Si Xiaoyan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Brain metastases
Cerebrospinal fluid
Penetration rate
T790M mutation
Third generation EGFR TKI
Structural optimization of diphenylpyrimidine scaffold as potent and selective epidermal growth factor receptor inhibitors against L858R/T790M resistance mutation in nonsmall cell lung cancer
期刊论文
2018, 卷号: 92, 期号: 6, 页码: 1988-1997
作者:
Yi, Yuanyuan
;
Wang, Luhong
;
Zhao, Dan
;
Huang, Shanshan
;
Wang, Changyuan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
EGFR T790M
inhibitors
NSCLC
pyrimidine
resistance
Primary and acquired EGFR T790M-mutant NSCLC patients identified by routine mutation testing show different characteristics but may both respond to osimertinib treatment
期刊论文
2018, 卷号: 423, 页码: 9-15
作者:
Li, Weihua
;
Qiu, Tian
;
Guo, Lei
;
Ling, Yun
;
Gao, Yibo
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2020/01/03
Non-small cell lung cancer
Primary EGFR T790M mutation
Acquired EGFR T790M mutation
Sensitizing EGFR mutation
Mutant allele frequency
Osimertinib in advanced or metastatic non-small cell lung cancer patients with EGFR T790M mutation after treatment with EGFR-TKI: Interim analysis of China cohort from the single-arm, open-label, international, multi-center real-world ASTRIS stud
会议论文
ANNALS OF ONCOLOGY, 2018-11-01
作者:
Zhou, Q.
;
Zhang, H.
;
Jiang, L.
;
Shi, Y.
;
Chen, Y.
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
Osimertinib in advanced or metastatic non-small cell lung cancer patients with EGFR T790M mutation after treatment with EGFR-TKI: Interim analysis of China cohort from the single-arm, open-label, international, multi-center real-world ASTRIS stud
期刊论文
2018, 卷号: 29, 页码: 158-158
作者:
Zhou, Q.
;
Zhang, H.
;
Jiang, L.
;
Shi, Y.
;
Chen, Y.
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Osimertinib (AZD9291) in Asia-Pacific Patients with T790M Mutation-Positive Advanced NSCLC: Open-Label Phase II Study Results
期刊论文
2017, 卷号: 12, 期号: 1, 页码: S1250-S1250
作者:
Zhou, Caicun
;
Wang, Mengzhao
;
Cheng, Ying
;
Chen, Yuan
;
Zhao, Yanqui
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
EGFR-TKI
T790M
osimertinib (AZD9291)
EGFR mutation
EGFR T790M ctDNA testing platforms and their role as companion diagnostics: Correlation with clinical outcomes to EGFR-TKIs
期刊论文
2017, 卷号: 403, 页码: 186-194
作者:
Liang, Zhiyong
;
Cheng, Ying
;
Chen, Yuan
;
Hu, Yanping
;
Liu, Wei-Ping
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
EGFR T790M mutation
Tyrosine kinase inhibitors
NSCLC
Drug resistance
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