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科研机构
复旦大学上海医学院 [11]
内容类型
期刊论文 [11]
发表日期
2019 [1]
2018 [1]
2016 [2]
2015 [2]
2013 [1]
2011 [2]
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专题:复旦大学上海医学院
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Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163
作者:
Li, Yali
;
Huang, Taomin
;
Lou, Bin
;
Ye, Deyong
;
Qi, Xiangyu
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/05
Sphingomyelin synthase 2
Inhibitor
ApoE KO mice
Atherosclerosis
Discovery of 4-Benzyloxybenzo[d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/db Mice
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 18
作者:
Mo, Mingguang
;
Yang, Jintong
;
Jiang, Xian-Cheng
;
Cao, Yu
;
Fei, Jinyu
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/05
Chinese hamster ovary-sphingomyelin synthase2 biospecific extraction and liquid chromatography with tandem mass spectrometry analysis for the prediction of bioactive components of Rhizoma Polygoni Cuspidati
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2016, 卷号: 39, 期号: 6
作者:
Dong, Jibin
;
Liang, Jianying
;
Xue, Ying
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Bioactive candidates
Biospecific extraction
Rhizoma Polygoni Cuspidati
Screening
Traditional Chinese medicine
Novel Dual Inhibitors of Secretory Phospholipase A(2) and Sphingomyelin Synthase: Design, Synthesis and Evaluation
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2016, 卷号: 13, 期号: 10
作者:
Gong, Haojun
;
Zhou, Lu
;
Ye, Deyong
;
Gao, Xing
;
Li, Yali
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/06
Atherosclerosis
secretory phospholipase A(2) (sPLA(2))
sphingomyelin synthase (SMS)
dual inhibitors
Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 18
作者:
Li, Ya-li
;
Qi, Xiang-yu
;
Jiang, Hui
;
Deng, Xiao-dong
;
Dong, Yan-ping
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/19
Sphingomyelin synthase
Inhibitor
Structure-based virtual screening
Molecular docking
Point mutagenesis
All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity
期刊论文
JOURNAL OF LIPID RESEARCH, 2015, 卷号: 56, 期号: 3
作者:
Ding, Tingbo
;
Kabir, Inamul
;
Li, Yue
;
Lou, Caixia
;
Yazdanyar, Amirfarbod
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/19
sphingomyelin synthase-related protein
sphingomyelin synthase 1
sphingomyelin synthase 2
mouse gene knockout
Sphingomyelin Synthase 2 Activity and Liver Steatosis: An Effect of Ceramide-Mediated Peroxisome Proliferator-Activated Receptor gamma 2 Suppression
期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2013, 卷号: 33, 期号: 7
作者:
Li, Yue
;
Dong, Jibin
;
Ding, Tingbo
;
Kuo, Ming-Shang
;
Cao, Guoqing
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/19
CD36
ceramide
liver lipids
liver steatosis
peroxisome proliferator-activated receptor gamma 2
sphingolipids
sphingomyelin
Molecular Modeling of the Three-Dimensional Structure of Human Sphingomyelin Synthase
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2011, 卷号: 29, 期号: 8
作者:
Zhang Ya
;
Lin Fu
;
Deng Xiaodong
;
Wang Renxiao
;
Ye Deyong
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/19
sphingomyelin synthase
molecular modeling
molecular dynamics
Subcellular Targeting Domains of Sphingomyelin Synthase 1 and 2
期刊论文
NUTRITION & METABOLISM, 2011, 卷号: 8
作者:
Yeang, Calvin
;
Ding, Tingbo
;
Chirico, William J.
;
Jiang, Xian-Cheng
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/19
Macrophage Sphingomyelin Synthase 2 Deficiency Decreases Atherosclerosis in Mice
期刊论文
CIRCULATION RESEARCH, 2009, 卷号: 105, 期号: 3
作者:
Liu, Jing
;
Huan, Chongmin
;
Chakraborty, Mahua
;
Zhang, Hongqi
;
Lu, Da
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
macrophage sphingomyelin synthase deficiency
sphingomyelin biosynthesis
cholesterol efflux
inflammation
atherosclerosis
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