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科研机构
复旦大学上海医学院 [20]
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期刊论文 [20]
发表日期
2019 [2]
2018 [4]
2017 [2]
2016 [1]
2015 [1]
2013 [2]
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专题:复旦大学上海医学院
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Functional Site Discovery From Incomplete Training Data: A Case Study With Nucleic Acid-Binding Proteins
期刊论文
FRONTIERS IN GENETICS, 2019, 卷号: 10
作者:
Wang, Wenchuan
;
LangIois, Robert
;
Langlois, Marina
;
Genchev, Georgi Z.
;
Wang, Xiaolei
收藏
  |  
浏览/下载:133/0
  |  
提交时间:2019/12/05
machine learning
protein sequence and structural analysis
multiple-instance learning
decision trees
semi supervised learning
protein function annotation
DNA binding proteins
RNA binding proteins
Combining a Fusion Inhibitory Peptide Targeting the MERS-CoV S2 Protein HR1 Domain and a Neutralizing Antibody Specific for the S1 Protein Receptor-Binding Domain (RBD) Showed Potent Synergism against Pseudotyped MERS-CoV with or without Mutations in RBD
期刊论文
VIRUSES-BASEL, 2019, 卷号: 11, 期号: 1
作者:
Wang, Cong
;
Hua, Chen
;
Xia, Shuai
;
Li, Weihua
;
Lu, Lu
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/12/05
MERS-CoV
RBD
mutation
peptide
neutralizing antibody
combination
Reduced selenium-binding protein 1 correlates with a poor prognosis in intrahepatic cholangiocarcinoma and promotes the cell epithelial-mesenchymal transition
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2018, 卷号: 10, 期号: 11
作者:
Zhang, Xin-Yu
;
Gao, Ping-Ting
;
Yang, Xuan
;
Cai, Jia-Bin
;
Ding, Guang-Yu
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Selenium-binding protein 1
intrahepatic cholangiocarcinoma
prognosis
epithelial-mesenchymal transition
Characterization of antibody-C1q interactions by Biolayer Interferometry
期刊论文
ANALYTICAL BIOCHEMISTRY, 2018, 卷号: 549
作者:
Zhou, Wei
;
Lin, Shanshan
;
Chen, Rongying
;
Liu, Jun
;
Li, Yali
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Monoclonal antibodies
C1q binding
Antigen binding
FC binding
Invasive potential of hepatocellular carcinoma is enhanced by loss of selenium-binding protein 1 and subsequent upregulation of CXCR4
期刊论文
AMERICAN JOURNAL OF CANCER RESEARCH, 2018, 卷号: 8, 期号: 6
作者:
Gao, Ping-Ting
;
Ding, Guang-Yu
;
Yang, Xuan
;
Dong, Rui-Zhao
;
Hu, Bo
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
Selenium-binding protein 1
CXCR4
epithelial-mesenchymal transition
hepatocellular carcinoma
Discovery of carbazole carboxamides as novel ROR gamma t inverse agonists
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148
作者:
Huang, Yafei
;
Yu, Mingcheng
;
Sun, Nannan
;
Tang, Ting
;
Yu, Fazhi
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Carbazole carboxamides
ROR gamma t inverse agonists
Th17 cells
Autoimmune diseases
Binding mode
T0001, a variant of TNFR2-Fc fusion protein, exhibits improved Fc effector functions through increased binding to membrane-bound TNFα.
期刊论文
PloS one, 2017, 卷号: 12, 期号: 5
作者:
Shen Yijun
;
Li Gang
;
Gu Chunying
;
Chen Ben
;
Chen Aihua
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Engineered Soluble Monomeric IgG1 Fc with Significantly Decreased Non-Specific Binding
期刊论文
FRONTIERS IN IMMUNOLOGY, 2017, 卷号: 8
作者:
Wang, Chunyu
;
Wu, Yanling
;
Wang, Lili
;
Hong, Binbin
;
Jin, Yujia
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
monomeric IgG1 Fc
non-specific binding
neonatal Fc receptor
half-life
monoclonal antibody
Efficient Inhibition of Hepatitis B Virus Infection by a preS1-binding Peptide
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:
Ye, Xiaoli
;
Zhou, Ming
;
He, Yonggang
;
Wan, Yanmin
;
Bai, Weiya
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Structural insights on the catalytic site protection of human carbonyl reductase 1 by glutathione
期刊论文
JOURNAL OF STRUCTURAL BIOLOGY, 2015, 卷号: 192, 期号: 1
作者:
Liang, Qingnan
;
Liu, Rui
;
Du, Shuqi
;
Ding, Yu
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
Human carbonyl reductase 1 (hCBR1)
Glutathione binding site
Substrate selectivity
Catalytic center protection
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