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科研机构
复旦大学上海医学院 [95]
内容类型
期刊论文 [92]
会议论文 [3]
发表日期
2019 [9]
2018 [8]
2017 [8]
2016 [10]
2015 [7]
2014 [10]
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Discovery, synthesis, biological evaluation and molecular docking study of (R)-5-methylmellein and its analogs as selective monoamine oxidase A inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 10
作者:
Lei, Xinsheng
;
Hu, Jin-Feng
;
Guan, Hui-Da
;
Wang, Chang-Hong
;
Huang, Chao
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/12/05
Natural product
5-Methylmellein
Synthetic analogs
Monoamine oxidase
Inhibitor
Synthesis and Preliminary Biological Evaluation of Two Fluoroolefin Analogs of Largazole Inspired by the Structural Similarity of the Side Chain Unit in Psammaplin A
期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 6
作者:
Zhang, Bingbing
;
Shan, Guangsheng
;
Zheng, Yinying
;
Yu, Xiaolin
;
Ruan, Zhu-Wei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/05
marine natural product
Largazole
Psammaplin A
HDAC inhibitors
luoro olefin
Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 3
作者:
Shi, Tian-Qi
;
Wang, Yan-Ting
;
Liu, Chang-Hong
;
Zhu, Hai-Liang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Benzimidazole
Benzsulfamide
Pyrazole
Tubulin
Inhibition
Apoptosis
Molecular docking
Synthesis and biological evaluation of novel 1-substituted 3-(3-phenoxyprop-1-yn-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amines as potent Bruton's tyrosine kinase (BTK) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2
作者:
Zheng, Nan
;
Hao, Qun
;
Lin, Kuaile
;
Pan, Jing
;
Li, Yingxia
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
BTK inhibitors
1-Substituted pyrazolo[3,4-d]pyrimidine
Inhibitory activity
B-cell lymphoblastic leukemia
Cytotoxicity
Design, synthesis and biological evaluation of novel indone derivatives as selective ER beta modulators
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 7
作者:
Liu, Xi-Xi
;
Tang, Mei-Lin
;
Zhong, Chen
;
Tang, Yun
;
Yu, Jian-Ming
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Resveratrol oligomer
ER beta
Breast cancer
SERM
Synthesis and biological evaluation of anthraquinone derivatives as allosteric phosphoglycerate mutase 1 inhibitors for cancer treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168
作者:
Huang, Ke
;
Jiang, Lulu
;
Liang, Ronghui
;
Li, Huiti
;
Ruan, Xiaoxue
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Phosphoglycerate mutase 1
Anthraquinone derivatives
Allosteric inhibitors
Cancer treatment
Synthesis and biological evaluation of dihydroquinazoline-2-amines as potent non-nucleoside reverse transcriptase inhibitors of wild-type and mutant HIV-1 strains
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 176
作者:
Jin, KaiJun
;
Sang, YaLi
;
Han, Sheng
;
De Clercq, Erik
;
Pannecouque, Christophe
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/05
Anti-HIV-1 activity
Dihydroquinazolines
DAPYs
Reverse transcriptase
Efavirenz
Etravirine
Synthesis and biological evaluation of Ginsenoside Compound K analogues as a novel class of anti-asthmatic agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 1
作者:
Ren, Sumei
;
Liu, Ruiqi
;
Wang, Yujie
;
Ding, Ning
;
Li, Yingxia
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/05
Ginsenoside Compound K
Asthma
Glycosylation
Saponin
IgE
Design, synthesis and biological evaluation of novel, orally bioavailable pyrimidine-fused heterocycles as influenza PB2 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162
作者:
Xiong, Jian
;
Wang, Jingjing
;
Hu, Guoping
;
Zhao, Weili
;
Li, Jianqi
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Influenza
Polymerase inhibitor
PB2
Drug design
Metabolic stability
Xanthone derivatives as phosphoglycerate mutase 1 inhibitors: Design, synthesis, and biological evaluation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8
作者:
Zhang, Shiyu
;
Wang, Penghui
;
Jiang, Lulu
;
Cao, Yang
;
Zhang, Xiaodan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Phosphoglycerate mutase 1
Inhibitors
Xanthone derivatives
Cancer cell metabolism
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