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科研机构
中南大学 [17]
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期刊论文 [17]
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2018 [2]
2015 [1]
2013 [4]
2012 [2]
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Galangin (GG) combined with cisplatin (DDP) to suppress human lung cancer by inhibition of STAT3-regulated NF-κB and Bcl-2/Bax signaling pathways
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 97, 页码: 213-224
作者:
Yu, Shuo
;
Gong, Lian-sheng*
;
Li, Nian-feng
;
Pan, Yi-feng
;
Zhang, Lun
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/12/03
MTT
3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide
GG
Galangin
DDP
cisplatin
STAT3
signal transducers and activation of transcription
LC
Lung cancer
MDR
multidrug resistance
NSCL
Cnon-small cell lung cancer
Bcl-2
B-cell leukemia/lymphoma 2
Bax
bcl-2-like protein
TRAIL
TNF-related apoptosis-inducing ligand
NF-κB
nuclear factor kappa-light-chain-enhancer of activated B cells
IκBα
inhibitor of NF-κBα
Cyto-c
cytochrome c
Lung cancer
Galangin
Cisplatin
p-STAT3/p65
Bcl-2
Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
SIRT1 is a regulator of autophagy: Implications in gastric cancer progression and treatment
期刊论文
FEBS Letters, 2015, 卷号: 589, 期号: 16, 页码: 2034-2042
作者:
Qiu, Guanglin
;
Li, Xuqi
;
Che, Xiangming
;
Wei, Chao
;
He, Shicai
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
GC
gastric cancer
SIRT1
silent mating type information regulation 1
HDACs
histone deacetylases
PCD
programmed cell death
TSC2
tuberous sclerosis complex 2
ATGs
autophagy-related genes
EMT
epithelial-mesenchymal transition
MDR
multidrug resistance
Gastric cancer
Silent mating type information regulation 1
Autophagy
Tumor suppressor
Tumor promoter
Molecular cloning and expression analysis of PDR1-like gene in ginseng subjected to salt and cold stresses or hormonal treatment
期刊论文
Plant Physiology and Biochemistry, 2013, 卷号: 71, 页码: 203-211
作者:
Zhang, Ru
;
Zhu, Jie
;
Cao, Hong-Zhe
;
An, Yan-Ru
;
Huang, Jing-Jia
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
ABA
ABC
ATP-binding cassette
CaMV
DIG
Environmental stresses
GFP
Gene expression
Hormones
JA
MDR
MDR-associated protein
MRP
MS
MeJA
Murashige and Skoog
NBD
ORF
PDR
Panax ginseng
Pleiotropic drug resistance transporter
RACE
SA
SAR
TMD
abscisic acid
cauliflower mosaic virus
digoxigenin
green fluorescent protein
jasmonic acid
methyl jasmonate
multidrug resistance
nucleotide binding domain
open reading frame
pleiotropic drug resistance
qRT-RCR
quantitative real-time PCR
rapid-amplification of cDNA end
salicylic acid
systemic acquired resistance
transmembrane domain
Silencing the EZH2 gene by RNA interference reverses the drug resistance of human hepatic multidrug-resistant cancer cells to 5-Fu
期刊论文
Life Sciences, 2013, 卷号: 92, 期号: 17-19, 页码: 896-902
作者:
Zhang, Yi
;
Liu, Guangpu
;
Lin, Changwei
;
Liao, Guoqing*
;
Tang, Bo
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/03
EZH2
Hepatocellular carcinoma
Multidrug resistance
MDR1
RNA interference
Triptolide inhibits the multidrug resistance in prostate cancer cells via the downregulation of MDR1 expression
期刊论文
Neoplasma, 2013, 卷号: 60, 期号: 6, 页码: 598-604
作者:
Guo, Q.
;
Nan, X. X.
;
Yang, J. R.*
;
Yi, L.
;
Liang, B. L.
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/03
MDR1
multidrug resistance
prostate cancer
triptolide
apoptosis
Survivin up-regulates the expression of breast cancer resistance protein (BCRP) through attenuating the suppression of p53 on NF-kappaB expression in MCF-7/5-FU cells.
期刊论文
The International Journal of Biochemistry & Cell Biology, 2013, 卷号: 45, 期号: 9, 页码: 2036-2044
作者:
Wang, Qing-ping
;
Wang, Yu
;
Wang, Xue-dong*
;
Mo, Xi-ming
;
Gu, Juan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
5-FU
5-fluorouracil
BCRP
Breast cancer resistance protein
MDR
MX
Multidrug resistance
NF-kappaB
Survivin
breast cancer resistance protein
mitoxantrone
multidrug resistance
p53
OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance
期刊论文
Biochemical Pharmacology, 2012, 卷号: 84, 期号: 6, 页码: 766-774
作者:
Ye-Hong Kuang
;
Jay P. Patel
;
Kamlesh Sodani
;
Chung-Pu Wu
;
Li-Qiu Liao
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
OSI-930
{N-(4-trifluoromethoxyphenyl)3-((quinolin-4-ylmethyl) amino) thiophene-2-carboxamide}
ABC
ATP binding cassette
ABCG2 (BCRP/MXR/ABCP)
ABC subfamily G member 2
MDR
multidrug resistance
P-gp
P-glycoprotein
ABCCs (MRPs)
ABC subfamily C member
RTK
receptor tyrosine kinases
KDR
kinase insert domain receptor
TKIs
tyrosine kinase inhibitors
IAAP
[125I]-iodoarylazidoprazosin
FTC
fumitremorgin C
MTT
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
DMSO
dimethylsulfoxide
OSI-930
ABC transporters
ABCG2
Multidrug resistance
Effects of curcumin on the pharmacokinetics of talinolol in human with ABCB1 polymorphism
期刊论文
Xenobiotica, the fate of foreign compounds in biological systems, 2012, 卷号: 42, 期号: 12, 页码: 1248-1254
作者:
He, X.
;
Mo, L.
;
Li, Z. -Y.
;
Tan, Z. -R.
;
Chen, Y.
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Curcumin
Multidrug resistance 1 (MDR1/ABCB1)
P-glycoprotein
Pharmacokinetics
Polymorphism
Talinolol
Synergistic Effect of Hyperthermia and Neferine on Reverse Multidrug Resistance in Adriamycin-resistant SGC7901/ADM Gastric Cancer Cells
期刊论文
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2011, 卷号: 31, 期号: 4, 页码: 488-496
作者:
Chenghui Huang 黄程辉
;
Yaping Li 李亚萍
;
Peiguo Cao 曹培国
;
Zhaoxia Xie 谢兆霞
;
Zhiqiang Qin 秦志强
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
gastric cancer
multidrug resistance
hyperthermia
Neferine
mdr-1
P-glycoprotein
adriamycin
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