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科研机构
昆明植物研究所 [35]
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期刊论文 [35]
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2020 [1]
2019 [7]
2018 [3]
2017 [2]
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Pharmacolo... [3]
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Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
作者:
Wang, Xue-Quan
;
Chen, Xue-Bing
;
Ye, Ping-Ting
;
Yang, Zhi-Xin
;
Bai, Meng-Jiao
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2020/03/18
3-Benzylcoumarin
Imidazolium salts
Biological evaluation
Cytotoxic activity
Structure-activity relationships
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts
期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:
Yang, Jun-Li
;
Ma, Yong-Hui
;
Li, Yan-Hua
;
Zhang, Yi-Peng
;
Tian, Hong-Chang
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/03/18
Synthesis and antitumor activity of aza-brazilan derivatives containing imidazolium salt pharmacophores
期刊论文
MEDCHEMCOMM, 2019, 卷号: 10, 期号: 6, 页码: 1027-1036
作者:
Huang, Mingqin
;
Duan, Shengzu
;
Ma, Xueqiong
;
Cai, Bicheng
;
Wu, Dongmei
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  |  
浏览/下载:76/0
  |  
提交时间:2019/07/29
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:
Deng, Guogang
;
Zhou, Bei
;
Wang, Jing
;
Chen, Zhuo
;
Gong, Liang
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  |  
浏览/下载:99/0
  |  
提交时间:2019/07/29
Diosgenin
Cholesterol
Dehydroepiandrosterone
Imidazolium salt
Antitumor activities
Structure-activity relationships
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:
Zhang, Yu
;
Goto, Masuo
;
Oda, Akifumi
;
Hsu, Pei-Ling
;
Guo, Ling-Li
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2019/07/29
aspidosperma-type
monoterpenoid indole alkaloids
antiproliferative activity
tubulin inhibitor
Bousigonia mekongensis
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:
Ye, Zhen-Nan
;
Yuan, Feng
;
Liu, Jie-Qing
;
Peng, Xing-Rong
;
An, Tao
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/07/29
4 beta HWE
Wnt signaling pathway
beta-catenin
colorectal cancer
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:
Lin, Xin
;
Tian, Dongsong
;
Fu, Yanhui
;
Li, Yanan
;
Huang, Liejun
收藏
  |  
浏览/下载:151/0
  |  
提交时间:2019/03/18
Polycyclic polyprenylated acylphloroglucinol
Chemical transformation
Cytotoxicity
Cell apoptosis
Cell cycle arrest
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
作者:
Hu, Jing
;
Li, Xingren
;
Tian, Weifeng
;
Lu, Yanting
;
Xu, Yuhui
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2019/03/18
adenanthin
adipogenesis
reactive oxygen species
obesity
3T3-L1
Discovery of novel wee1 inhibitors via structure-based virtual screening and biological evaluation
期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2018, 卷号: 32, 期号: 9, 页码: 901-915
作者:
Li, Yaping
;
Pu, Yinglan
;
Liu, Hui
;
Zhang, Li
;
Liu, Xingyong
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2018/11/06
Wee1 inhibitors
Pharmacophore model
Molecular docking
Virtual screening
Molecular dynamics simulation
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer
期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:
Wang, Jing-Nan
;
Zhang, Zhi-Rong
;
Che, Yun
;
Yuan, Zu-Yang
;
Lu, Zhi-Liang
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2018/07/16
Acetyl-macrocalin B
reactive oxygen species
p38 MAPK
apoptosis
Chk1
Chk2
G2
M phase arrest
NSCLC
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