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科研机构
上海药物研究所 [119]
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期刊论文 [118]
会议论文 [1]
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2022 [1]
2021 [6]
2019 [4]
2018 [11]
2017 [12]
2016 [11]
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The regulatory role of MiR-203 in oxidative stress induced cell injury through the CBS/H2S pathway
期刊论文
NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2022, 卷号: 118, 页码: 31-38
作者:
Zhang, Qiuyan
;
Shen, Zhuqing
;
Shen, Yaqi
;
Ma, Muye
;
Jue, Hao
收藏
  |  
浏览/下载:227/0
  |  
提交时间:2022/01/04
Cerebral infarction
Cystathionine-beta-synthase
miRNA-203
Hydrogen sulfide
Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:
Lu, Tian
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  |  
浏览/下载:42/0
  |  
提交时间:2021/12/01
Hippo pathway
TEAD3
Covalent inhibitor
Palmitoylation inhibitor
Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 906, 页码: 8
作者:
Xiao, Meng-Chao
;
Qian, Hui
;
Huang, Chen-Kai
;
Zheng, Bai-Nan
;
Yan, Fang-Zhi
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  |  
浏览/下载:51/0
  |  
提交时间:2021/11/04
Imatinib
Autophagy
Hepatocarcinoma
Sorafenib
Synergetic effect
A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-κB pathway
期刊论文
Cancer Cell International, 2021, 卷号: 21, 期号: 1
作者:
Gao,Xuejie
;
Li,Bo
;
Ye,Anqi
;
Wang,Houcai
;
Xie,Yongsheng
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2021/06/11
Multiple myeloma
Anti-tumor activity
NF-κB
A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-kappa B pathway
期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 10
作者:
Gao, Xuejie
;
Li, Bo
;
Ye, Anqi
;
Wang, Houcai
;
Xie, Yongsheng
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
Multiple myeloma
Anti-tumor activity
NF-kappa B
A novel mouse model for liver metastasis of prostate cancer reveals dynamic tumour-immune cell communication
期刊论文
CELL PROLIFERATION, 2021, 页码: 12
作者:
Liu, Kaiyuan
;
Jing, Na
;
Wang, Deng
;
Xu, Penghui
;
Wang, Jinming
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2021/08/17
liver metastasis
metastasis‐
associated immune cell
metastatic microenvironment
prostate cancer
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
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  |  
浏览/下载:43/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1587-1595
作者:
Zhang, Kai-li
;
Shen, Qian-qian
;
Fang, Yan-fen
;
Sun, Yi-ming
;
Ding, Jian
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
PRC2
EZH2-EED
AZD9291
miR-34a
non-canonical base pairing
Orthogonal assays for the identification of inhibitors of the single-stranded nucleic acid binding protein YB-1
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 5, 页码: 997-1007
作者:
Trevarton, Alexander J.
;
Zhou, Yan
;
Yang, Dehua
;
Rewcastle, Gordon W.
;
Flanagan, Jack U.
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Cancer
YB-1
Luciferase
AlphaScreen
Transcription factor
Single-stranded DNA
2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019, 卷号: 19, 页码: 13
作者:
Li, Wuguo
;
Zhang, Qing
;
Chen, Kaotan
;
Sima, Zhenhua
;
Liu, Jingli
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Polygonum cuspidatum
2-Ethoxystypandrone
Hepatocellular carcinoma
Cancer stem cells
STAT3 signaling pathway
Cancer stemness inhibitor
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