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科研机构
上海药物研究所 [56]
内容类型
期刊论文 [55]
会议论文 [1]
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2021 [3]
2020 [7]
2019 [3]
2018 [6]
2017 [8]
2016 [7]
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Synthesis and bioactivity studies of covalent inhibitors derived from (-)-Chaetominine
期刊论文
JOURNAL OF MOLECULAR STRUCTURE, 2021, 卷号: 1241, 页码: 14
作者:
Zhou, Xian
;
Feng, Xuexin
;
Wang, Dachi
;
Chen, Deheng
;
Wu, Gaoxing
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2021/08/17
Chaetominine
Cellular growth inhibition
Cancer cell line
Covalent warhead
A five-dimensional data collection strategy for multicomponent discovery and characterization in Traditional Chinese Medicine: Gastrodia Rhizoma as a case study
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1653, 页码: 12
作者:
Zhu, Haodong
;
Wu, Xingdong
;
Huo, Jiangyan
;
Hou, Jinjun
;
Long, Huali
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2021/11/04
Gastrodia Rhizoma
Multidimensional data acquisition
Offline 2D-LC-IMS-DIA MS
MS
Neutral loss (NLs)
Collision cross section (CCS)
Marine furanocembranoids-inspired macrocycles enabled by Pd-catalyzed unactivated C(sp(3))-H olefination mediated by donor/donor carbenes
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:
Hao, Jiping
;
Guo, Xueying
;
He, Shijun
;
Xu, Zhongliang
;
Chen, Lu
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  |  
浏览/下载:31/0
  |  
提交时间:2021/05/24
Characterization of anti-BCG benz[alpha]anthraquinones and new siderophores from a Xinjiang desert-isolated rare actinomyceteNocardiasp. XJ31
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2020, 卷号: 104, 期号: 19, 页码: 8267-8278
作者:
Zhang, Li
;
Zhang, Jingyu
;
Ren, Biao
;
Lu, Wanying
;
Hou, Chengjian
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  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
Xinjiang desert
Nocardiasp
Anti-BCG
Brasiliquinone
Nocardimicin
Design of Pt/SAPO-11 bifunctional catalyst with superior metal-acid balance constructedviaa novel one-step pre-loading strategy for enhancingn-dodecane hydroisomerization performance
期刊论文
CATALYSIS SCIENCE & TECHNOLOGY, 2020, 卷号: 10, 期号: 17, 页码: 5953-5963
作者:
Du, Yanyan
;
Yao, Heliang
;
Hu, Wenjing
;
Tan, Yangchun
;
Xu, Yanhui
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/24
Optimizing chemical reaction conditions using deep learning: a case study for the Suzuki-Miyaura cross-coupling reaction
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 16, 页码: 2269-2277
作者:
Fu, Zunyun
;
Li, Xutong
;
Wang, Zhaohui
;
Li, Zhaojun
;
Liu, Xiaohong
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  |  
浏览/下载:36/0
  |  
提交时间:2020/12/24
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
Transformations of Aryl Ketones via Ligand-Promoted C-C Bond Activation
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 7
作者:
Li, Hanyuan
;
Ma, Biao
;
Liu, Qi-Sheng
;
Wang, Mei-Ling
;
Wang, Zhen-Yu
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/12/24
aryl ketones
borylation
C-C bond activation
Pd catalysis
Highly selective monitoring of in-source fragmentation sapogenin product ions in positive mode enabling group-target ginsenosides profiling and simultaneous identification of seven Panax herbal medicines
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2020, 卷号: 1618, 页码: 11
作者:
Zhang, Chun-xia
;
Wang, Xiao-yan
;
Lin, Zhao-zhou
;
Wang, Hong-da
;
Qian, Yue-xin
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
In-source fragmentation
Ginsenoside
Selective ion monitoring
Characteristic chromatogram
Panax
Traditional Chinese medicine formula
An integrated strategy for holistic quality identification of Chinese patent medicine:Liuwei Dihuang Pillsas a case study
期刊论文
PHYTOCHEMICAL ANALYSIS, 2020, 页码: 15
作者:
Wang, Xia
;
Wu, Wenyong
;
Zhang, Jianqing
;
Gao, Lei
;
Zhang, Linlin
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  |  
浏览/下载:67/0
  |  
提交时间:2020/12/24
characteristic compound
holistic identification
LC-MS
LWDHP
multivariate statistical analysis
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