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科研机构
上海药物研究所 [52]
内容类型
期刊论文 [52]
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2021 [1]
2020 [10]
2019 [5]
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Transcriptome Regulation by Oncogenic ALK Pathway in Mammalian Cortical Development Revealed by Single-Cell RNA Sequencing
期刊论文
CEREBRAL CORTEX, 2021, 卷号: 31, 期号: 8, 页码: 3911-3924
作者:
Mao, Rui
;
Zhang, Xiaoyun
;
Kong, Youyong
;
Wu, Shanshan
;
Huo, Hai-qin
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/08/17
anaplastic lymphoma kinase
cerebral organoid
neurodevelopment
neural progenitor cell
single-cell RNA sequencing
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex
期刊论文
FRONTIERS IN PSYCHIATRY, 2020, 卷号: 11, 页码: 11
作者:
Liu, Wei
;
Li, Qian
;
Ye, Binglu
;
Cao, Hang
;
Shen, Fuyi
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/12/21
nitrous oxide (N2O)
depression
mPFC
burst firing
neuronal nitric oxide synthase (nNOS)
BDNF
Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex
期刊论文
FRONTIERS IN PSYCHIATRY, 2020, 卷号: 11, 页码: 11
作者:
Liu, Wei
;
Li, Qian
;
Ye, Binglu
;
Cao, Hang
;
Shen, Fuyi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
nitrous oxide (N2O)
depression
mPFC
burst firing
neuronal nitric oxide synthase (nNOS)
BDNF
Extracellular Vesicle-Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models
期刊论文
CIRCULATION, 2020, 卷号: 142, 期号: 6, 页码: 556-574
作者:
Yang, Li
;
Han, Bing
;
Zhang, Zhiting
;
Wang, Shuguo
;
Bai, Ying
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2020/12/24
circular RNA
extracellular vesicles
MeCP2 protein
neuronal plasticity
primate
stroke
An optically active isochroman-2H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tao, Ling-xue
;
Ji, Sha-sha
;
Szaloki, Dora
;
Kovacs, Tibor
;
Mandi, Attila
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
neurodegeneration
oxidative stress
apoptosis
MAPK pathway
PI3K
Akt pathway
SH-SY5Y neuroblastoma cells
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Development of Novel N-hydroxypyridone Derivatives as Potential Anti-Ischemic Stroke Agents
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 3, 页码: 1051-1067
作者:
Hu, Linghao
;
Feng, Hongxuan
;
Zhang, Hongguang
;
Yu, Songda
;
Zhao, Qinyuan
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
A fluorogenic probe for tracking GSH flux in developing neurons
期刊论文
CHEMICAL COMMUNICATIONS, 2020, 卷号: 56, 期号: 4, 页码: 515-518
作者:
Zong, Haichao
;
Peng, Jiayi
;
Li, Xiao-Rong
;
Liu, Meng
;
Hu, Yongzhou
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Antiepileptic geissoschizine methyl ether is an inhibitor of multiple neuronal channels
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Xie, Zhu-qing
;
Tian, Xiao-ting
;
Zheng, Yue-ming
;
Zhan, Li
;
Chen, Xue-qin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
geissoschizine methyl ether
Uncaria rhynchophyll
antiepileptic drug
hippocampal neurons
action potential
nicotinic acetylcholine receptors
voltage-gated ion channels
mouse seizure model
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