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科研机构
上海药物研究所 [27]
内容类型
期刊论文 [27]
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2021 [4]
2020 [1]
2018 [1]
2017 [1]
2015 [3]
2012 [2]
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New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 7
作者:
Wang, Yi
;
Fang, Sui
;
Wu, Yan
;
Cheng, Xi
;
Zhang, Lei-ke
收藏
  |  
浏览/下载:110/0
  |  
提交时间:2021/08/17
SARS-CoV-2
envelope protein (2-E)
cation channel
high-throughput screening (HTS)
anti-virus
TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia
期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 378, 期号: 1, 页码: 20-30
作者:
Wang, Yu
;
He, Yang
;
Yang, Feipu
;
Abame, Melkamu Alemu
;
Wu, Chunhui
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/11/04
Neonatal cortical astrocytes possess intrinsic potential in neuronal conversion in defined media
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Zeng, Peng
;
Hua, Qiu-hong
;
Gong, Jun-yuan
;
Shi, Chang-jie
;
Pi, Xiao-ping
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/05/24
cortical astrocytes
neonatal
neuronal conversion
insulin
heterogeneity
Antiepileptic geissoschizine methyl ether is an inhibitor of multiple neuronal channels
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Xie, Zhu-qing
;
Tian, Xiao-ting
;
Zheng, Yue-ming
;
Zhan, Li
;
Chen, Xue-qin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
geissoschizine methyl ether
Uncaria rhynchophyll
antiepileptic drug
hippocampal neurons
action potential
nicotinic acetylcholine receptors
voltage-gated ion channels
mouse seizure model
Characteristics of hERG and hNav1.5 channel blockade by sulcardine sulfate, a novel anti-arrhythmic compound
期刊论文
European journal of pharmacology, 2018, 卷号: 844, 页码: 130-138
作者:
Chen, Weihai
;
Gan, Lu
;
Wang, Yiping
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Structural insights into the potency of SK channel positive modulators
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Nam, Young-Woo
;
Orfali, Razan
;
Liu, Tingting
;
Yu, Kunqian
;
Cui, Meng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
TREK1 channel blockade induces an antidepressant-like response synergizing with 5-HT1A receptor signaling
期刊论文
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2015, 卷号: 25, 期号: 12, 页码: 2426-2436
作者:
Ye, Dongqing
;
Li, Yang
;
Zhang, Xiangrong
;
Guo, Fei
;
Geng, Leiyu
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
TWIK-related mechano-gated K+ channel (TREK1)
Antidepressant
SID1900
5-HT1A receptor
Chronic unpredictable mild stress (CUMS)
Brain derived neurotrophic factor (BDNF)
Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails
期刊论文
CELL RESEARCH, 2015, 卷号: 25, 期号: 9, 页码: 1013-1024
作者:
Fu, Yanbin
;
Huang, Chenwen
;
Xu, Xinxiu
;
Gu, Haifeng
;
Ye, Youqiong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
transdifferentiation
cardiac reprogramming
cardiomyocyte
fibroblast
chemical cocktail
small molecule compounds
directreprogrammingofmousefibroblastsintocardiomyocyteswithchemicalcocktails
期刊论文
cellresearch, 2015, 卷号: 25, 期号: 9, 页码: 1013
作者:
Qiu Zilong
;
Xie Xin
;
Fu Yanbin
;
Huang Chenwen
;
Xu Xinxiu
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
PLURIPOTENT STEM-CELLS
IN-VIVO
CARDIAC FIBROBLASTS
PROGENITOR CELLS
SOMATIC-CELLS
ADULT HEART
TGF-BETA
DIFFERENTIATION
GENERATION
PROMOTES
transdifferentiation
cardiac reprogramming
cardiomyocyte
fibroblast
chemical cocktail
small molecule compounds
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