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科研机构
上海药物研究所 [76]
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期刊论文 [75]
会议论文 [1]
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2021 [2]
2020 [3]
2019 [2]
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2017 [3]
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A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Characterization and quantitative determination of henagliflozin metabolites in humans
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 192, 页码: 8
作者:
Chen, Zhendong
;
Li, Liang
;
Zhan, Yan
;
Zhang, Yifan
;
Liu, Haiyan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Henagliflozin
Metabolism
LC-MS/MS
Liquid chromatography-tandem mass spectrometric assay for TPN171 in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 191, 页码: 8
作者:
Zhang, Mengqi
;
Liu, Haiming
;
He, Jiajin
;
Gui, Yuzhou
;
Qian, Hongjie
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/24
TPN171
LC-MS/MS
Human plasma
Protein precipitation
Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9
作者:
Qiu, Yanan
;
Tang, Chongzhuang
;
Li, Ranran
;
Cao, Sumin
;
Zhang, Yuqiang
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/24
LC-MS
MS
N-oxide
stability
sutetinib
Qualitative and quantitative determination of anaprazole and its major metabolites in human plasma
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 183, 页码: 10
作者:
Tang, Chongzhuang
;
Li, Liang
;
Ma, Xifeng
;
Wang, Jin
;
Chen, Bo
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  |  
浏览/下载:82/0
  |  
提交时间:2020/07/01
Metabolite identification
LC-MS/MS
UPLC-UV/Q-TOF
Anaprazole
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:
Liu, Xiaoyun
;
Li, Wei
;
Zhang, Yifan
;
Jian, Yong
;
Zhao, Qianyu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
LC-MS/MS
Alflutinib
AST2818
Pharmacokinetics
Human plasma
Simultaneous determination of imrecoxib and its two active metabolites in plasma of hepatic impairment patients by liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2019, 卷号: 1122, 页码: 58-63
作者:
Hou, Xiangyu
;
Dai, Xiaojian
;
Yang, Yong
;
Zhang, Yifan
;
Zhong, Dafang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
Imrecoxib
Imrecoxib active metabolites
Pharmacokinetics
LC-MS/MS
Human
Moderate impairment
Systematic profiling and comparison of the lipidomes from Panax ginseng, P. quinquefolius, and P. notoginseng by ultrahigh performance supercritical fluid chromatography/high-resolution mass spectrometry and ion mobility-derived collision cross section measurement
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1548, 页码: 64-75
作者:
Shi, Xiaojian
;
Yang, Wenzhi
;
Qiu, Shi
;
Hou, Jinjun
;
Wu, Wanying
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Lipidomics
Ultrahigh performance supercritical fluid chromatography
Ion mobility spectroscopy
Collision cross section
Panax
Quality control
Adduct ion-targeted qualitative and quantitative analysis of polyoxypregnanes by ultra-high pressure liquid chromatography coupled with triple quadrupole mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2017, 卷号: 145, 页码: 127-136
作者:
Wu, X.
;
Zhu, Lin
;
Ma, Jiang
;
Ye, Yang
;
Lin, Ge
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Adduct ion formation
Marsdenia tenacissima
Polyoxypregnane
Triple quadrupole mass spectrometry
A UPLC/MS/MS method for determination of protosappanin B in rat plasma and its application of a pharmacokinetic and bioavailability study
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2017, 卷号: 31, 期号: 7
作者:
Chen, Wei-Ying
;
Zhou, Xian-Zhen
;
Wu, Li-Lan
;
Wu, Yun-Shan
;
Wang, Shu-Mei
收藏
  |  
浏览/下载:229/0
  |  
提交时间:2019/01/08
Bioavailability
Pharmacokinetic
protosappanin B
UPLC-MS/MS
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