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Structural basis of ligand recognition and self-activation of orphan GPR52 期刊论文
NATURE, 2020, 页码: 21
作者:  Lin, Xi;  Li, Mingyue;  Wang, Niandong;  Wu, Yiran;  Luo, Zhipu
收藏  |  浏览/下载:198/0  |  提交时间:2020/07/01
DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening 期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 17, 期号: 5, 页码: 478-495
作者:  Wan, Fangping;  Zhu, Yue;  Hu, Hailin;  Dai, Antao;  Cai, Xiaoqing
收藏  |  浏览/下载:34/0  |  提交时间:2020/07/01
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein 期刊论文
NATURE, 2018, 卷号: 558, 期号: 7711, 页码: 553-+
作者:  Kang, Yanyong;  Kuybeda, Oleg;  de Waal, Parker W.;  Mukherjee, Somnath;  Van Eps, Ned
收藏  |  浏览/下载:82/0  |  提交时间:2019/01/08
Chemical Diversity in the G Protein-Coupled Receptor Superfamily 期刊论文
TRENDS IN PHARMACOLOGICAL SCIENCES, 2018, 卷号: 39, 期号: 5, 页码: 494-512
作者:  Vass, Marton;  Kooistra, Albert J.;  Yang, Dehua;  Stevens, Raymond C.;  Wang, Ming-Wei
收藏  |  浏览/下载:40/0  |  提交时间:2019/01/08
Design and synthesis of aryloxypropanolamine as beta(3)-adrenergic receptor antagonist in cancer and lipolysis 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 150, 页码: 757-770
作者:  Jin, Jiyu;  Miao, Chunxiao;  Wang, Zhilong;  Zhang, Wanli;  Zhang, Xiongwen
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08
Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors 期刊论文
CELL, 2017, 卷号: 170, 期号: 3, 页码: 457-+
作者:  Zhou, X. Edward;  He, Yuanzheng;  de Waal, Parker W.;  Gao, Xiang;  Kang, Yanyong
收藏  |  浏览/下载:31/0  |  提交时间:2019/01/08
N-glycosylation of the beta(2) adrenergic receptor regulates receptor function by modulating dimerization 期刊论文
FEBS JOURNAL, 2017, 卷号: 284, 期号: 13, 页码: 2004-2018
作者:  Li, Xiaona;  Zhou, Mang;  Huang, Wei;  Yang, Huaiyu
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Rearrangement of a polar core provides a conserved mechanism for constitutive activation of class B G protein-coupled receptors 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 24, 页码: 9865-9881
作者:  Yin, Yanting;  de Waal, Parker W.;  He, Yuanzheng;  Zhao, Li-Hua;  Yang, Dehua
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective alpha(1A)-Adrenoceptor Antagonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 20, 页码: 9489-9502
作者:  Guo, Diliang;  Li, Jing;  Lin, Henry;  Zhou, Yu;  Chen, Ying
收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective alpha(1A)-Adrenoceptor Antagonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 8, 页码: 3826-3839
作者:  Zhao, Fei;  Li, Jing;  Chen, Ying;  Tian, Yanxin;  Wu, Chenglin
收藏  |  浏览/下载:41/0  |  提交时间:2019/01/08


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