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CORC

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Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK 期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:  Elksnis, Andris;  Schiffer, Tomas A.;  Palm, Fredrik;  Wang, Yun;  Cen, Jing
收藏  |  浏览/下载：23/0  |  提交时间：2021/12/01
Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Liu, Lu
收藏  |  浏览/下载：81/0  |  提交时间：2021/08/17
Drug interaction of ningetinib and gefitinib involving CYP1A1 and efflux transporters in non-small cell lung cancer patients 期刊论文
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 页码: 13
作者:  Liu, Lu;  Wang, Qian;  Xie, Cen;  Xi, Ning;  Guo, Zitao
收藏  |  浏览/下载：59/0  |  提交时间：2020/12/24
Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins 期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 35, 期号: 5, 页码: 456-465
作者:  Liu, Xiaoyun;  Feng, Dan;  Zheng, Mingyue;  Cui, Yongmei;  Zhong, Dafang
收藏  |  浏览/下载：15/0  |  提交时间：2020/12/21
Metabolism-based structure optimization: Discovery of a potent and orally available tyrosine kinase ALK inhibitor bearing the tetracyclic benzo[b]carbazolone core (vol 26, pg 5399, 2016) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 1
作者:  Han, Mei;  Wang, Chengyan;  Ji, Yinchun;  Song, Zilan;  Xing, Li
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01
UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis 期刊论文
NATURE, 2019, 卷号: 571, 期号: 7763, 页码: 127-+
作者:  Wang, Xiongjun;  Liu, Ruilong;  Zhu, Wencheng;  Chu, Huiying;  Yu, Hua
收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15
作者:  Jin, Nan;  Bi, Aiwei;  Lan, Xiaojing;  Xu, Jun;  Wang, Xiaomin
收藏  |  浏览/下载：63/0  |  提交时间：2020/07/01
metabolismanddispositionofpyrotinibinhealthymalevolunteerscovalentbindingwithhumanplasmaprotein 期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 7, 页码: 980
作者:  Meng Jian;  Liu Xiaoyun;  Ma Sheng;  Zhang Hua;  Yu Songda
收藏  |  浏览/下载：2/0  |  提交时间：2020/07/01
Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Meng, Jian;  Liu, Xiao-Yun;  Ma, Sheng;  Zhang, Hua;  Yu, Song-da
收藏  |  浏览/下载：101/0  |  提交时间：2019/01/08
Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 6, 页码: 1048-1063
作者:  Zhong, Chen-chun;  Chen, Feng;  Yang, Jun-ling;  Jia, Wei-wei;  Li, Li
收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08

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