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科研机构
上海药物研究所 [92]
内容类型
期刊论文 [91]
会议论文 [1]
发表日期
2021 [9]
2020 [10]
2019 [8]
2018 [12]
2017 [6]
2016 [9]
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Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:
Fan, Shijie
;
Yue, Liyan
;
Wan, Wei
;
Zhang, Yuanyuan
;
Zhang, Bidong
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/12/16
covalent modification
probes
proteome
LC3
post-translational modification
Research Progress in Chinese Herbal Medicines for Treatment of Sepsis: Pharmacological Action, Phytochemistry, and Pharmacokinetics
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 20, 页码: 27
作者:
Cheng, Chen
;
Yu, Xuan
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/12/16
antiseptic actions
Chinese herbal medicines
material basis
Qingwen Baidu decoction
Shengfu injection
Shengmai
sepsis
Xuanbai Chengqi decoction
XueBiJing injection
Structures of full-length glycoprotein hormone receptor signalling complexes
期刊论文
NATURE, 2021, 页码: 24
作者:
Duan, Jia
;
Xu, Peiyu
;
Cheng, Xi
;
Mao, Chunyou
;
Croll, Tristan
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/11/04
The Novel Chinese Medicine JY5 Formula Alleviates Hepatic Fibrosis by Inhibiting the Notch Signaling Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 15
作者:
Fu, Yadong
;
Xiao, Zhun
;
Tian, Xiaoting
;
Liu, Wei
;
Xu, Zhou
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/01/04
traditional Chinese medicine
JY5 formula
fuzheng huayu
hepatic fibrosis
notch signaling pathway
Alteration of twinfilin1 expression underlies opioid withdrawal-induced remodeling of actin cytoskeleton at synapses and formation of aversive memory
期刊论文
MOLECULAR PSYCHIATRY, 2021, 页码: 19
作者:
Wang, Yu-Jun
;
Yu, Chuan
;
Wu, Wei-Wei
;
Ju, Yun-Yue
;
Liu, Yao
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  |  
浏览/下载:81/0
  |  
提交时间:2021/06/11
Identification of the absorbed ingredients and metabolites in rats after an intravenous administration of Tanreqing injection using high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 16
作者:
Xie, Like
;
Wang, Yangyang
;
Yin, Hao
;
Li, Jiajia
;
Xu, Zhou
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/05/24
COVID‐
19
metabolic profiles
quadrupole time‐
of‐
flight mass spectrometry
Tanreqing injection
traditional Chinese medicine
Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855
作者:
Zhou, Yu
;
Fu, Yan
;
Yin, Wanchao
;
Li, Jian
;
Wang, Wei
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:
Zhang, Rui
;
Li, Heng
;
Zhang, Xianglei
;
Li, Jian
;
Su, Haixia
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
PDE4 inhibitors
Tetrahydroisoquinoline
Antipsoriasis
CST6 protein and peptides inhibit breast cancer bone metastasis by suppressing CTSB activity and osteoclastogenesis
期刊论文
THERANOSTICS, 2021, 卷号: 11, 期号: 20, 页码: 9821-9832
作者:
Li, Xiaoxun
;
Liang, Yajun
;
Lian, Cheng
;
Peng, Fangli
;
Xiao, Yansen
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/04
Breast cancer
Bone metastasis
Osteoclastogenesis
CST6
Peptide drug
Harnessing Genomic Stress for Antitumor Immunity
期刊论文
ANTIOXIDANTS & REDOX SIGNALING, 2020, 页码: 23
作者:
Pu, Congying
;
Tao, Siyao
;
Xu, Jun
;
Huang, Min
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
genomic stress
cancer
genomic instability
antitumor immunity
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