CORC

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CORC

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Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma 期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:  Chen, Zi-qi;  Cao, Zhe-rui;  Wang, Yi;  Zhang, Xi;  Xu, Lan
收藏  |  浏览/下载：53/0  |  提交时间：2021/12/16
CYH33  MYC  P300  BET  B cell lymphoma  PI3K  
Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 42, 页码: 18005-18013
作者:  Chai, Xianzhi;  Han, Hai-Hao;  Sedgwick, Adam C.;  Li, Na;  Zang, Yi
收藏  |  浏览/下载：41/0  |  提交时间：2021/05/24
Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 16, 页码: 6
作者:  Su, Zhicheng;  Yang, Tingyuan;  Wang, Jie;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载：28/0  |  提交时间：2020/12/24
EGFR  NSCLC  C797S  
Exploring Conformational Change of Adenylate Kinase by Replica Exchange Molecular Dynamic Simulation 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 118, 期号: 5, 页码: 1009-1018
作者:  Wang, Jinan;  Peng, Cheng;  Yu, Yuqu;  Chen, Zhaoqiang;  Xu, Zhijian
收藏  |  浏览/下载：42/0  |  提交时间：2020/07/01
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models 期刊论文
SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12
作者:  Liao, Ping;  Qiu, Yunguang;  Mo, Yiqing;  Fu, Jie;  Song, Zhenpeng
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01
PD-L1 expression levels on tumor cells affect their immunosuppressive activity 期刊论文
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 5, 页码: 5399-5407
作者:  Zheng, Yang;  Fang, You-Chen;  Li, Jing
收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01
Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR(L858R/T790M/C797S) 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 6, 页码: 869-873
作者:  Li, Qiannan;  Zhang, Tao;  Li, Shiliang;  Tong, Linjiang;  Li, Junyu
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01
EGFR  mutant  inhibitor  C797S  
Exploring binding mechanisms of VEGFR2 with three drugs lenvatinib, sorafenib, and sunitinib by molecular dynamics simulation and free energy calculation 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 5, 页码: 934-948
作者:  Wang, Yu;  Peng, Cheng;  Wang, Guimin;  Xu, Zhijian;  Luo, Yongfeng
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
Temperature- and rigidity-mediated rapid transport of lipid nanovesicles in hydrogels 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 12, 页码: 5362-5369
作者:  Yu, Miaorong;  Song, Wenyi;  Tian, Falin;  Dai, Zhuo;  Zhu, Quanlei
收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01

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